Sulindac EP Impurity B-d3 CAS 250608-67-4
| CAS No. | 250608-67-4 |
| Molecular Formula | - |
| Molecular Weight | 375.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 375.43 g/mol gives Sulindac EP Impurity B-d3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Sulindac EP Impurity B-d3 (CAS 250608-67-4) is a certified pharmaceutical impurity reference standard with the molecular formula C20H14D3FO4S and a molecular weight of 375.43 g/mol.
Sulindac EP Impurity B-d3 (C20H14D3FO4S) contains deuterium isotope labeling, a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Sulindac EP Impurity B-d3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14D3FO4S |
| Molecular Weight | 375.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Sulindac Standards
- Sulindac Impurity N94 (CAS CATO-CP155194)
- Sulindac Sulfone (CAS 59864-04-9)
- Sulindac EP Impurity B (CAS 59973-80-7)
- Sulindac Sulfone-d7 (CAS CATO-C4X-293019)
- Sulindac EP Impurity D (CAS 134439-52-4)
- (R)-Sulindac Methyl Ester (CAS 929081-61-8)
- Sulindac Sulfide Methyl Ester (CAS 106647-49-8)
- Sulindac Impurity 1 (CAS 68299-97-8)
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- Leukotriene B4-dimethyl Amide (CAS 83024-92-4)
- Acetyl Tetrapeptide-5 (CAS 820959-17-9)
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