Sulindac EP Impurity B CAS 59973-80-7
| CAS No. | 59973-80-7 |
| Molecular Formula | C20H17FO4S |
| Molecular Weight | 372.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sulindac EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Sulindac EP Impurity B (CAS 59973-80-7), a pharmacopoeial impurity reference standard (molecular formula C20H17FO4S, MW 372.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Sulindac EP Impurity B (C20H17FO4S) contains a flavonoid core, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C20H17FO4S |
| Molecular Weight | 372.41 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Sulindac Standards
- Sulindac Sulfone (CAS 59864-04-9)
- Sulindac Impurity N94 (CAS CATO-CP155194)
- Sulindac EP Impurity D (CAS 134439-52-4)
- Sulindac EP Impurity B-d3 (CAS 250608-67-4)
- Sulindac Sulfide Methyl Ester (CAS 106647-49-8)
- Sulindac Sulfone-d7 (CAS CATO-C4X-293019)
- (R)-Sulindac Methyl Ester (CAS 929081-61-8)
- Sulindac Impurity 1 (CAS 68299-97-8)
Recommended Standards
- Arctigenin (CAS 7770-78-7)
- Ethyl 2-(4-((3-(methylsulfonyl)-1,2,4-thiadiazol-5-yl)oxy)phenoxy)propanoate (CAS 1000573-04-5)
- Tetrahydrocurcumin (CAS 36062-04-1)
- Pentamidine Diamidoxime (CAS 101689-95-6)
- Loxoprofen Impurity 78 (CAS CATO-C4X-148878)
- Deferasirox Impurity 18 (CAS 1395346-29-8)
- Cefuroxime Axetil Impurity 14 (CAS CATO-C4X-143614)
- 4-Amino-2-hydroxy-3-methylbenzoic acid (CAS 855362-50-4)
- 6-(Difluoromethyl)pyridazine-4-carboxylic acid (CAS 2231735-75-2)
- 3-(2,3-dimethoxybenzoyl)-1,3-thiazolidine-2-thione (CAS 144344-71-8)
- (S)-3-(allylsulfonyl)-8-nitro-1,2,3,4,4a,5-hexahydrobenzo[b]pyrazino[1,2-d][1,4]oxazine (CAS CATO-C3D-262490)
- 2-Hydroxy-1-(5-methyl-2-furyl)ethanone (CAS 28201-53-8)
- (3S)-3-{[2-(ethylamino)-2-methylpropanamido]methyl}-5-methylhexanoic acid (CAS 1786569-61-6)
- Semaglutide Impurity 123 (CAS 71997-93-8)
Why CATO?
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