Ofloxacin EP Impurity E CAS 82419-52-1
| CAS No. | 82419-52-1 |
| Molecular Formula | C17H18FN3O4 |
| Molecular Weight | 347.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Ofloxacin EP Impurity E (CAS 82419-52-1) is a certified pharmaceutical impurity reference standard with the molecular formula C17H18FN3O4 and a molecular weight of 347.34 g/mol.
Ofloxacin EP Impurity E (C17H18FN3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Ofloxacin EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H18FN3O4 |
| Molecular Weight | 347.34 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ofloxacin Standards
Recommended Standards
- Ciprofloxacin impurity 51 (CAS CATO-C4X-136251)
- Levofloxacin Impurity 22 (CAS 82419-46-3)
- Ciprofloxacin Impurity 41 (CAS CATO-C4X-136241)
- Levofloxacin EP Impurity B (CAS 117707-40-1)
- Epinephrine /Adrenaline Impurity 137 (CAS 2771193-18-9)
- Ibutilide Impurity 8 (CAS CATO-C4X-21108)
- Faropenem Impurity 16 (CAS CATO-C4X-128916)
- 2-(2-hYdroxybenzoyl)hydrazinecarboximidamide (CAS 6005-61-4)
- 2,3-Dichloro-N,N-dimethylaniline (CAS 58566-65-7)
- 81029-07-4 Gallium(III) perchlorate hydrate, 13.5-15.5% Ga MFCD00167156 (CAS 81029-07-4)
- 2-(Benzyloxy)-4-fluorobenzonitrile (CAS 503293-06-9)
- 5-Oxo-5-(phenylamino)pentanoic acid (CAS 5414-99-3)
- 1-[4-(3-Aminocyclopentyl)-1-piperazinyl]ethanone (CAS 1519552-41-0)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com