4-(2,5-Difluoro-4-nitrophenoxy)-3-iodopyridin-2-amine CAS 1345854-92-3
| CAS No. | 1345854-92-3 |
| Molecular Formula | C11H6F2IN3O3 |
| Molecular Weight | 393.08 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(2,5-Difluoro-4-nitrophenoxy)-3-iodopyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 4-(2,5-Difluoro-4-nitrophenoxy)-3-iodopyridin-2-amine (CAS 1345854-92-3), a certified reference material (molecular formula C11H6F2IN3O3, MW 393.08 g/mol) for analytical method development and quality control.
Structurally, 4-(2,5-Difluoro-4-nitrophenoxy)-3-iodopyridin-2-amine (C11H6F2IN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 393.08 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H6F2IN3O3 |
| Molecular Weight | 393.08 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 3 |
Related Difluoro Standards
- 2,4-Difluoro-6-((2-fluoro-4-iodophenyl)amino)benzoic acid (CAS 934665-14-2)
- 3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzoic Acid (CAS 391211-97-5)
- 4-(Difluoro(3,4,5-trifluorophenoxy)methyl)-4'-propyl-1,1'-biphenyl (CAS 337456-92-5)
- 2-((3,5-Difluoro-4-hydroxyphenyl)amino)-8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6(5H)-one (CAS 501437-28-1)
- 3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-Benzoyl fluoride (CAS 934664-19-4)
- Benzyl 3,3-difluoro-4-(iodomethyl)-2-oxopyrrolidine-1-carboxylate (CAS 1823264-85-2)
- Methyl 1-(2,4-Difluoro-phenyl)-5-((4-tert-butyl-thiosemicarbazono)methyl)-1H-pyrazole-4-carboxylate (CAS 264233-05-8)
- 4-(Difluoro(3,4,5-trifluorophenoxy)methyl)-4'-ethyl-1,1'-bi(cyclohexane) (CAS 208338-49-2)
Recommended Standards
- 1,4-Bis(4-bromophenyl)-1H-pyrazol-5-amine (CAS 1202028-75-8)
- 1,3-Bis(4-bromophenyl)-1H-pyrazol-5-amine (CAS 618098-21-8)
- 8-(Benzyloxy)-5,7-dibromoquinoline (CAS 84165-50-4)
- 3,4-Dichloro-N-[2,4-dichloro-5-(propan-2-yloxy)phenyl]benzamide (CAS 338961-14-1)
- 2,5-Diisopropylnitrobenzene (CAS 10472-64-7)
- (2R,3S,4S,5S,6R)-2-fluoro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 2713-54-4)
- Methyl 4-((benzo[d]thiazole-2-carboxamido)methyl)piperidine-1-carboxylate (CAS 1235205-09-0)
- (3S,4S)-4-Benzylpyrrolidine-3-carboxylic acid hydrochloride (CAS 2137134-80-4)
- 1-(1-Methoxypropyl)-1H-indazol-6-amine (CAS 1337881-41-0)
- (S)-1-(5-Fluoro-2-iodophenyl)ethan-1-ol (CAS 1454847-96-1)
- 4-[(Benzenesulfonyl)methyl]-6-chloro-2-(pyridin-3-yl)pyrimidine (CAS 303147-31-1)
- 2-(1-Phenyl-1h-pyrazol-4-yl)acetonitrile (CAS 51412-23-8)
- 3-Methoxy-4-[(2-methyl-1,3-thiazol-4-yl)methoxy]benzaldehyde (CAS 795290-89-0)
- Semaglutide impurity 204 (CAS CATO-C4X-2226204)
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