4-Methyl Erlotinib CAS 1346601-52-2
| CAS No. | 1346601-52-2 |
| Molecular Formula | C23H25N3O4 |
| Molecular Weight | 407.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Methyl Erlotinib is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Methyl Erlotinib (CAS 1346601-52-2), a certified reference material (molecular formula C23H25N3O4, MW 407.46 g/mol) for analytical method development and quality control.
Structurally, 4-Methyl Erlotinib (C23H25N3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 407.46 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Methyl Erlotinib under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H25N3O4 |
| Molecular Weight | 407.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- Erlotinib impurity 136 (CAS 1058651-74-3)
- Erlotinib impurity 138 (CAS 1318600-03-1)
- Erlotinib Impurity 6 (CAS 882420-22-6)
- Erlotinib Impurity 91 (CAS 1354727-63-1)
- Erlotinib Impurity 3 (CAS 183321-82-6)
- Erlotinib Impurity 15 (CAS CATO-C4X-106915)
- Erlotinib Impurity 2 (CAS 183321-85-9)
- Erlotinib Impurity 103 (CAS 299912-61-1)
Recommended Standards
- N-(4-(2-((1-Cyanocyclohexyl)amino)-2-oxoethoxy)phenyl)-2-methoxybenzamide (CAS 852684-81-2)
- Galanthamine Impurity 28 (CAS CATO-C4X-143528)
- N-(3-Allyl-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)-2-(2,5-dioxopyrrolidin-1-yl)acetamide (CAS 865175-74-2)
- Roxadustat Impurity 169 (CAS 2731734-01-1)
- (3,5-Dimethylphenyl)(oxazol-2-yl)methanone (CAS 898784-52-6)
- 2-(2-Isopropoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160264-82-3)
- (R)-3-Amino-4-(m-tolyl)butanoic acid hydrochloride (CAS 331846-94-7)
- 2-Chloro-1-(1-ethyl-1H-indol-3-yl)ethanone (CAS 38693-16-2)
- 3-Fluoro-2-hydroxybenzene-1-sulfonyl chloride (CAS 1261649-13-1)
- 4-(2,5-Dimethyl-1H-pyrrol-1-yl)-N-(4-morpholinophenyl)butanamide (CAS 1251558-10-7)
- 2-((6-Methoxypyridazin-3-yl)methylene)hydrazinecarboxamide (CAS 89854-30-8)
- 2-Iodo-N-(tert-butoxycarbonyl)indole (CAS 99275-46-4)
- n-(Cyclopropylmethyl)-2-methyl-1-phenylpropan-1-amine (CAS 1156207-40-7)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com