Azelastine-13C,d3 N-Oxide (Mixture of Diastereomers) CAS 1346602-76-3
| CAS No. | 1346602-76-3 |
| Molecular Formula | C21[13C]H21D3ClN3O2 |
| Molecular Weight | 401.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Azelastine-13C,d3 N-Oxide (Mixture of Diastereomers) (CAS 1346602-76-3), a certified reference material (molecular formula C21[13C]H21D3ClN3O2, MW 401.91 g/mol) for analytical method development and quality control.
Owing to deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Azelastine-13C,d3 N-Oxide (Mixture of Diastereomers) is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 401.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21[13C]H21D3ClN3O2 |
| Molecular Weight | 401.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Azelastine Standards
- (S)-Azelastine N-Oxide (Mixture of Diastereomers) (CAS 1346617-06-8)
- (R)-Azelastine N-Oxide (Mixture of Diastereomers) (CAS 1346617-18-2)
- Azelastine USP Related Compound F (CAS 640279-88-5)
- Azelastine impurity 66 (CAS CATO-C4X-139666)
- Azelastine Impurity 72 (CAS CATO-C4X-139672)
- Azelastine-d3 (CAS 758637-88-6)
- Azelastine-13C,d3 (CAS 1217019-80-1)
- (R)-Azelastine (CAS 143228-84-6)
Recommended Standards
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