Ketotifen EP Impurity E CAS 1346603-71-1
| CAS No. | 1346603-71-1 |
| Molecular Formula | C19H19NOS |
| Molecular Weight | 309.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ketotifen EP Impurity E (CAS 1346603-71-1, C19H19NOS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ketotifen EP Impurity E (C19H19NOS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ketotifen EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H19NOS |
| Molecular Weight | 309.43 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Ketotifen Standards
- Ketotifen (CAS 34580-13-7)
- Ketotifen EP Impurity F (Mixture of Enol and Ketone) (CAS 34580-09-1)
- Ketotifen Impurity 20 (CAS CATO-C4X-204620)
- Ketotifen Impurity 28 (CAS CATO-C4X-204628)
- Ketotifen Impurity 15 (CAS CATO-C4X-204615)
- Ketotifen Impurity 23 (CAS 111428-56-9)
- Ketotifen EP Impurity G (CAS 43076-16-0)
- Ketotifen Impurity 19 (CAS 34580-20-6)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com