Benzoyl 3-chlorobenzoyl peroxide CAS 13495-28-8
| CAS No. | 13495-28-8 |
| Molecular Formula | C14H9ClO4 |
| Molecular Weight | 276.67 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Benzoyl 3-chlorobenzoyl peroxide (CAS 13495-28-8), a pharmacopoeial impurity reference standard (molecular formula C14H9ClO4, MW 276.67 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Benzoyl 3-chlorobenzoyl peroxide (C14H9ClO4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H9ClO4 |
| Molecular Weight | 276.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1960 |
| Halogen Content | Cl-containing |
Related Benzoyl Standards
- Benzoyl 4-chlorobenzoyl Peroxide (CAS 790-45-4)
- (E)-2-benzoyl-3-(4-(dimethylamino)phenyl)acrylonitrile (CAS 101220-35-3)
- 2-Benzoyl-3-methylnaphthalene-1,4-dione (CAS 17579-92-9)
- 3-(4-Benzoyl-1-piperazinyl)-3-oxopropanoic acid (CAS 896509-15-2)
- 3-Benzoyl-1-phenyl-1H-pyrazole-4-carbaldehyde (CAS 400900-22-3)
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- 1-Benzoyl-2-hydroxy-7-thia-1-azaspiro[4.4]Nonan-9-one (CAS 69392-35-4)
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Recommended Standards
- Sofosbuvir Impurity 61 (CAS 1496551-72-4)
- 4-Chloro-7-fluoro-2-(4-fluorophenyl)quinazoline (CAS 885277-44-1)
- 2-(5-Chloro-2,3-dioxo-2,3-dihydro-1h-indol-1-yl)-n-(prop-2-yn-1-yl)acetamide (CAS 1020956-98-2)
- 4-Chloro-7-fluoro-2-(2-fluorophenyl)quinazoline (CAS 885277-58-7)
- Paroxetine Impurity 51 (CAS CATO-C4X-103551)
- Ulipristal Impurity 24 (CAS CATO-C4X-191524)
- Glutamic acid Impurity 3 (CAS CATO-C4X-28623)
- 3,3-Difluoro-4-Methyl-2-Oxopentanoic Acid (CAS 165544-39-8)
- Lornoxicam impurity 60 (CAS 123252-96-0)
- Chlorpheniramine Impurity 32 (CAS 854863-55-1)
- (S)-(4-Bromophenyl)(2-(4-chlorophenyl)piperazin-1-yl)methanone hydrochloride (CAS 2132392-81-3)
- 6-Bromo-5-chloro-3,4-dihydronaphthalen-1(2H)-one (CAS 1273663-89-0)
- BAL30072 Impurity 5 (CAS 102507-49-3)
- Semaglutide Impurity 7 (CAS CATO-C4X-22267)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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