Glutamic acid Impurity 3 CAS CATO-C4X-28623
| CAS No. | CATO-C4X-28623 |
| Molecular Formula | C16H20ClNO5 |
| Molecular Weight | 341.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Glutamic acid Impurity 3 (CAS CATO-C4X-28623), a pharmacopoeial impurity reference standard (molecular formula C16H20ClNO5, MW 341.79 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Glutamic acid Impurity 3 (C16H20ClNO5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Glutamic acid Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20ClNO5 |
| Molecular Weight | 341.79 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Glutamic Standards
- Glutamic acid Impurity 2 (CAS 51865-66-8)
- Glutamic acid Impurity 1 (CAS 13726-52-8)
- Glutamic Acid Impurity 4 (CAS 1417526-05-6)
- Glutamic acid Impurity 10 (CAS 67278-32-4)
- Glutamic acid impurity 8 (CAS 67278-37-9)
- L-Glutamic acid, 4-(2-naphthalenylmethyl)-, (4R)- (CAS 207497-67-4)
- Glutamic acid Impurity 4 (CAS 57444-70-9)
- Glutamic acid impurity 5 (CAS 87039-96-1)
Recommended Standards
- Lornoxicam Impurity 98 (CAS CATO-C4X-201698)
- Belumosudil Impurity 44 (CAS CATO-C4X-298844)
- Lornoxicam Impurity 2 (CAS 70374-38-8)
- Oxazepam impurity 6 (CAS CATO-C4X-30906)
- Doxapram EP Impurity B (CAS 1688-76-2)
- Venetoclax Impurity 115 (CAS CATO-C4X-2495115)
- Diquafosol Impurity 22 (CAS CATO-C4X-214922)
- 5-Acetamido-2-aminobenzoic acid (CAS 50670-83-2)
- 3-Amino-1-(4-methylpiperazin-1-yl)propan-1-one dihydrochloride (CAS 1049744-54-8)
- Tert-butyl (6-azabicyclo[3.2.1]Octan-3-yl)carbamate (CAS 2138167-45-8)
- (S)-3-(2-bromophenyl)piperidine hydrochloride (CAS 2416257-97-9)
- 5'-Bromo-1'-ethenyl-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-2'-one (CAS 1788054-77-2)
- Ethyl 2-cyclododecylideneacetate (CAS 1903-26-0)
- Palmitoyl Tetrapeptide-7 (CAS 221227-05-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com