Vericiguat Impurity 11 CAS 1350653-29-0
| CAS No. | 1350653-29-0 |
| Molecular Formula | C23H17F2N9 |
| Molecular Weight | 457.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Vericiguat Impurity 11 (CAS 1350653-29-0) is a certified pharmaceutical impurity reference standard with the molecular formula C23H17F2N9 and a molecular weight of 457.44 g/mol.
Vericiguat Impurity 11 (C23H17F2N9) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H17F2N9 |
| Molecular Weight | 457.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 9 |
Related Vericiguat Standards
- Vericiguat Impurity 23 (CAS CATO-C4X-289623)
- Vericiguat Impurity 28 (CAS CATO-C4X-289628)
- Vericiguat Impurity 79 (CAS CATO-C4X-289679)
- Vericiguat Impurity 81 (CAS CATO-C4X-289681)
- Vericiguat Impurity 86 (CAS CATO-C4X-289686)
- Vericiguat Impurity 95 (CAS CATO-C4X-289695)
- Vericiguat Impurity 33 (CAS CATO-C4X-289633)
- Vericiguat Impurity 58 (CAS CATO-C4X-289658)
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- (Glu（Obzl）-NCA） (CAS 13822-45-2)
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