(4-(4-Methoxyphenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone CAS 866154-40-7
| CAS No. | 866154-40-7 |
| Molecular Formula | C24H22F3N3O3 |
| Molecular Weight | 457.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 457.44 g/mol gives (4-(4-Methoxyphenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(4-(4-Methoxyphenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone (CAS 866154-40-7) is a high-purity analytical reference standard with the molecular formula C24H22F3N3O3 and a molecular weight of 457.44 g/mol.
Based on its molecular formula C24H22F3N3O3, (4-(4-Methoxyphenyl)piperazin-1-yl)(4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)methanone contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 457.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H22F3N3O3 |
| Molecular Weight | 457.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Methoxyphenyl Standards
- N-(4-methoxyphenyl)-6-oxo-4-(trifluoromethyl)-1-(3-(trifluoromethyl)phenyl)-1,6-dihydropyridazine-3-carboxamide (CAS 478067-11-7)
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- 6-((4-(4-Methoxyphenyl)-5-((2-oxo-2-(piperidin-1-yl)ethyl)thio)-4H-1,2,4-triazol-3-yl)methyl)pyrimidine-2,4(1H,3H)-dione (CAS 852152-81-9)
- 4-Methoxyphenyl 2-O-Acetyl-3-O-allyl-4,6-O-benzylidene-β-D-glucopyranoside (CAS 1477956-18-5)
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Recommended Standards
- 4-({[2-(1-methyl-1H-1,3-benzodiazol-2-yl)acetamido]imino}methyl)phenyl 3-nitrobenzoate (CAS 1302983-86-3)
- Cefixime Impurity 45 (CAS CATO-C4X-113945)
- L-Amygdalin (CAS 29883-16-7)
- Calcium Levofolinate EP Impurity I (CAS 31690-11-6)
- 3-Aminopiperidine-3-carboxamide (CAS 1516025-73-2)
- 9-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-2-yl)-9H-purin-6-amine (CAS 51549-32-7)
- 2-(Quinolin-4-yloxy)ethan-1-amine (CAS 34256-23-0)
- (R)-3-(Hydroxymethyl)pyrrolidine (CAS 110013-18-8)
- Diethyl 2-(furan-2-ylmethylene)malonate (CAS 17448-96-3)
- Ethyl 2-hydroxycyclopropane-1-carboxylate (CAS 1780168-09-3)
- 4-(((4-Methoxyphenyl)amino)methylene)-2,4-dihydro-3H-pyrazol-3-one (CAS 338777-73-4)
- 3-(4-Bromo-2-chlorophenoxy)propane-1-sulfonyl chloride (CAS 1407337-40-9)
- Benzyl (4-chlorophenyl)carbamate (CAS 6622-16-8)
- Des-[Gly]31-Semaglutide (CAS CATO-C4X-2226156)
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