Vericiguat Impurity 33 CAS CATO-C4X-289633
| CAS No. | CATO-C4X-289633 |
| Molecular Formula | C23H19F2N9 |
| Molecular Weight | 459.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Vericiguat Impurity 33.
As a process- or degradation-related impurity, Vericiguat Impurity 33 (CAS CATO-C4X-289633, C23H19F2N9) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Vericiguat Impurity 33 (C23H19F2N9) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Vericiguat Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H19F2N9 |
| Molecular Weight | 459.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 9 |
Related Vericiguat Standards
- Vericiguat Impurity 11 (CAS 1350653-29-0)
- Vericiguat Impurity 23 (CAS CATO-C4X-289623)
- Vericiguat Impurity 28 (CAS CATO-C4X-289628)
- Vericiguat Impurity 79 (CAS CATO-C4X-289679)
- Vericiguat Impurity 81 (CAS CATO-C4X-289681)
- Vericiguat Impurity 86 (CAS CATO-C4X-289686)
- Vericiguat Impurity 95 (CAS CATO-C4X-289695)
- Vericiguat Impurity 58 (CAS CATO-C4X-289658)
Recommended Standards
- Oxytetracycline EP Impurity C (CAS 7647-65-6)
- (S)-2-(2-aminoacetamido)-3-(4-(2-(((S)-1-carboxy-2-(4-hydroxyphenyl)ethyl)amino)-2-oxoethoxy)phenyl)propanoic acid (CAS CATO-CPTD788499)
- Sulpiride Impurity 21 (CAS 2267259-70-9)
- 2-(1-(2-((N-Ethylcyclopropanecarboxamido)methyl)-4-(trifluoromethyl)phenyl)-6-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid (CAS 1420071-13-1)
- Levocetirizine Impurity 75 (CAS CATO-C4X-108375)
- Encorafenib Impurity 11 (CAS CATO-C4X-32411)
- Galantamine EP Impurity D (CAS 664995-65-7)
- 6-Aminopyridine-2,4(1H,3H)-dione (CAS 901768-65-8)
- Methyl 2-(1,2,3,4-tetrahydroisoquinolin-4-yl)acetate hydrochloride (CAS 16261-33-9)
- Cefotaxime Impurity 22 (CAS CATO-C4X-120122)
- tert-Butyl (6-methyl-5-nitropyridin-3-yl)carbamate (CAS 1219948-26-1)
- 2-[4-(propan-2-yl)-1,3-thiazol-2-yl]acetonitrile (CAS 637015-75-9)
- 2,3,5-Trifluoropyridin-4-amine (CAS 105252-95-7)
- Peptide Impurity 70 TFA Salt (CAS CATO-CPTD788570)
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