5-Chloro-4-morpholinopyridine-3-sulfonamide CAS 1352496-85-5
| CAS No. | 1352496-85-5 |
| Molecular Formula | C9H12ClN3O3S |
| Molecular Weight | 277.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-4-morpholinopyridine-3-sulfonamide (CAS 1352496-85-5), molecular formula C9H12ClN3O3S and molecular weight 277.73 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-4-morpholinopyridine-3-sulfonamide (C9H12ClN3O3S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-4-morpholinopyridine-3-sulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12ClN3O3S |
| Molecular Weight | 277.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-5-(morpholinosulfonyl)pyridin-4-amine (CAS 1352507-24-4)
- N-(3-Chloro-4-cyano-5-isothiazolyl)-3-methylbenzenecarboxamide (CAS 159978-14-0)
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- 5-Chloro-3-(morpholinosulfonyl)pyridin-2-amine (CAS 1858255-77-2)
- 4-Chloro-N-hydrazinocarbonylmethyl-N-methyl-benzenesulfonamide (CAS 565192-26-9)
- 7-Chloro-2-methyl-3-(thiazol-2-yl)quinazolin-4(3H)-one (CAS 338794-10-8)
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Recommended Standards
- Methyl 4-chlorothieno[2,3-c]quinoline-6-carboxylate (CAS 1269468-16-7)
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- n-(1h-Benzo[d]imidazol-2-yl)-5-chlorothiophene-2-carboxamide (CAS 156840-74-3)
- Methyl 4-chlorothieno[3,2-c]quinoline-6-carboxylate (CAS 1269468-11-2)
- Methyl 4-acetyl-1-methyl-1H-pyrrole-2-carboxylate (CAS 85795-19-3)
- (S)-2-(6-Chloropyridin-3-yl)-4-((1-methoxypropan-2-yl)oxy)-N-(6-methylpyridin-3-yl)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide (CAS 1257051-62-9)
- 3-Chloro-2-[(difluoromethyl)sulfanyl]-5-(trifluoromethyl)pyridine (CAS 478246-09-2)
- 3-Bromo-4-(difluoromethoxy)benzene-1-sulfonyl chloride (CAS 1550696-74-6)
- (-)-Ci-Cdp1 (CAS 128050-92-0)
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- 7-Hydroxy-3-methyl-5-oxo-N-propyl-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide (CAS 898412-38-9)
- (R)-2-(bromomethyl)-1,4-dioxane (CAS 2287191-41-5)
- 3-(3-Bromophenyl)-1-(m-tolyl)propan-1-one (CAS 898781-97-0)
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