5-Chloro-3-(morpholinosulfonyl)pyridin-2-amine CAS 1858255-77-2
| CAS No. | 1858255-77-2 |
| Molecular Formula | C9H12ClN3O3S |
| Molecular Weight | 277.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-3-(morpholinosulfonyl)pyridin-2-amine (CAS 1858255-77-2), molecular formula C9H12ClN3O3S and molecular weight 277.73 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C9H12ClN3O3S, 5-Chloro-3-(morpholinosulfonyl)pyridin-2-amine contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 277.73 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Chloro-3-(morpholinosulfonyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12ClN3O3S |
| Molecular Weight | 277.73 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-4-morpholinopyridine-3-sulfonamide (CAS 1352496-85-5)
- 3-Chloro-5-(morpholinosulfonyl)pyridin-4-amine (CAS 1352507-24-4)
- N-(3-Chloro-4-cyano-5-isothiazolyl)-3-methylbenzenecarboxamide (CAS 159978-14-0)
- 2-(2-Chloro-6-methylthieno[3,2-d]pyrimidin-4-yl)pyrimidin-5-amine (CAS 1632286-27-1)
- 4-Chloro-N-hydrazinocarbonylmethyl-N-methyl-benzenesulfonamide (CAS 565192-26-9)
- 7-Chloro-2-methyl-3-(thiazol-2-yl)quinazolin-4(3H)-one (CAS 338794-10-8)
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Recommended Standards
- 1-(4-Chlorophenyl)-3-(3-cyanothiophen-2-yl)urea (CAS 338777-41-6)
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- n-(1h-Benzo[d]imidazol-2-yl)-5-chlorothiophene-2-carboxamide (CAS 156840-74-3)
- 3-(4-Chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-7-thiol (CAS 722456-34-0)
- 4-Bromo-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine (CAS 1083181-71-8)
- (2R,5R)-pyrrolidine-2,5-dicarboxylic acid (CAS 93713-35-0)
- 3-(Piperidin-3-yl)-1H-pyrazol-4-amine (CAS 1515044-96-8)
- 4-Fluoro-N,N-dimethyl-3-(trimethylsilyl)aniline (CAS 493024-41-2)
- 3-(3-Methoxyphenyl)-1H-pyrazole-4-carbaldehyde (CAS 874991-12-5)
- Ethyl 4-acetamidopiperidine-1-carboxylate (CAS 208179-77-5)
- Promestriene Impurity 9 (CAS 2575516-67-3)
- 4-Chloro-2-(2,6-dichlorophenyl)-7-fluoro-3H-imidazo[4,5-c]pyridine (CAS 1334411-84-5)
- 2-Methyl-3-(1H-pyrazol-5-yl)pyrazine (CAS 195447-81-5)
- Semaglutide impurity 214 (CAS CATO-C4X-2226214)
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