(R)-4-(4-Bromophenyl)pyrrolidin-2-one CAS 1353143-39-1
| CAS No. | 1353143-39-1 |
| Molecular Formula | C10H10BrNO |
| Molecular Weight | 240.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies (R)-4-(4-Bromophenyl)pyrrolidin-2-one (CAS 1353143-39-1), a certified reference material (molecular formula C10H10BrNO, MW 240.10 g/mol) for analytical method development and quality control.
The molecular framework of (R)-4-(4-Bromophenyl)pyrrolidin-2-one (C10H10BrNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), (R)-4-(4-Bromophenyl)pyrrolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H10BrNO |
| Molecular Weight | 240.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- 3-(3-bromophenyl)pyrrolidin-2-one (CAS 1004294-74-9)
- 1-(3-Bromophenyl)pyrrolidin-3-one (CAS 1096881-40-1)
- 1-(2-Bromophenyl)pyrrolidin-3-one (CAS 1096881-67-2)
- 4-(3-Bromophenyl)pyrrolidin-2-one (CAS 1105187-44-7)
- 4-(2-Bromophenyl)pyrrolidin-2-one (CAS 1171825-24-3)
- 2-[(3-bromophenyl)methyl]-3-hydroxypropanenitrile (CAS 1274682-30-2)
- 5-(3-Bromophenyl)pyrrolidin-2-one (CAS 1314757-72-6)
- 2-[(2-bromophenyl)methyl]-3-hydroxypropanenitrile (CAS 1339252-58-2)
Recommended Standards
- 4-Bromo-5-methoxy-7-methyl-1H-indole (CAS 1352393-65-7)
- 2-(7-Bromo-1H-indazol-3-yl)ethanamine (CAS 1360962-95-3)
- 7-Bromo-3,4-dihydroisoquinoline-2(1H)-carbaldehyde (CAS 1350411-25-4)
- 2-(4-Bromo-1H-indazol-3-yl)ethanamine (CAS 1360970-26-8)
- 2-Bromo-3-fluoro-4-hydroxybenzaldehyde (CAS 1807171-16-9)
- 4-(Difluoromethyl)-5-iodo-3-nitro-2-(trifluoromethoxy)pyridine (CAS 1804733-85-4)
- 3,5-Dibromo-1-methylpyridin-4(1H)-one (CAS 2683-35-4)
- 2-[4-(Hydroxymethyl)cyclohex-3-en-1-yl]propan-2-ol (CAS 5502-74-9)
- 2-(Cyclopropoxymethyl)isonicotinonitrile (CAS 2289532-65-4)
- 2-bromo-2-nitro-3-{[3-(trifluoromethyl)benzoyl]oxy}propyl 3-(trifluoromethyl)benzoate (CAS 244081-64-9)
- (S)-Methyl 2-amino-3-(1H-pyrazol-1-yl)propanoate (CAS 740736-19-0)
- 5-(5-Chlorothiophen-2-yl)-1H-pyrazole-3-carboxylic acid (CAS 890621-34-8)
- 5-(4-Chlorophenyl)-6-(trifluoromethyl)pyrimidine-2,4-diamine (CAS 2263-96-9)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com