4-Amino-2-(6-chlorooxazolo[5,4-b]pyridin-2-yl)phenol CAS 1354751-03-3
| CAS No. | 1354751-03-3 |
| Molecular Formula | C12H8ClN3O2 |
| Molecular Weight | 261.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Amino-2-(6-chlorooxazolo[5,4-b]pyridin-2-yl)phenol.
CATO supplies 4-Amino-2-(6-chlorooxazolo[5,4-b]pyridin-2-yl)phenol (CAS 1354751-03-3), a certified reference material (molecular formula C12H8ClN3O2, MW 261.66 g/mol) for analytical method development and quality control.
The molecular framework of 4-Amino-2-(6-chlorooxazolo[5,4-b]pyridin-2-yl)phenol (C12H8ClN3O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-Amino-2-(6-chlorooxazolo[5,4-b]pyridin-2-yl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H8ClN3O2 |
| Molecular Weight | 261.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 4-Amino-5-chloro-1-((2R,6R)-6-(hydroxymethyl)-1,4-dioxan-2-yl)pyrimidin-2(1H)-one (CAS 132062-65-8)
- 4-Amino-1-((2R,3S,4R,5R)-3-chloro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one (CAS 58461-30-6)
- 7-Amino-2-(4-chlorophenyl)[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-one (CAS 1354764-81-0)
- 5-Amino-1-(2-chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS 1416345-60-2)
- 7-Amino-6-(5-chloropyridin-2-yl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-one (CAS 1881330-63-7)
- 2-amino-8-(3-chlorophenyl)-6,9-dihydro-1H-purin-6-one (CAS 857524-98-2)
- 3-[(1Z)-2-Amino-1,2-dicyanoeth-1-en-1-yl]-1-(4-chlorophenyl)urea (CAS 865658-74-8)
- 3-Amino-5-(4-chlorophenyl)-1,5-dihydro-6H-pyrazolo[4,3-c]pyridazin-6-one (CAS 338405-68-8)
Recommended Standards
- Methyl 4-chloroimidazo[1,2-a]quinoxaline-8-carboxylate (CAS 1452864-18-4)
- 3-Chloro-4-nitrobenzophenone (CAS 131822-44-1)
- 5-((7-Chloro-1H-indol-3-yl)methylene)imidazolidine-2,4-dione (CAS 1627591-09-6)
- 5-Chloro-N-(1h-indazol-3-yl)furan-2-carboxamide (CAS 1258676-97-9)
- 8-Amino-4-(4-fluorobenzyl)-2H-1,4-benzoxazin-3(4H)-one (CAS 1018570-68-7)
- N-(2-Hydroxyethyl)-N-methylbenzenesulfonamide (CAS 59724-60-6)
- 6-Chloro-4-cyclopropyl-3-fluoro-2-methylpyridine (CAS 1821293-65-5)
- 3-Chloro-4-(trifluoromethoxy)benzaldehyde (CAS 83279-39-4)
- 4-Bromo-3-isopropylanisole (CAS 34881-45-3)
- N-(6-(tert-butyl)-3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-2-cyanoacetamide (CAS 560072-41-5)
- 3-(Pyridin-3-yl)-4,5-dihydro-1,2-oxazole-5-carboxylic acid (CAS 264606-31-7)
- N1-(Benzo[d][1,3]dioxol-5-ylmethyl)-N2-(3-chloro-4-methylphenyl)oxalamide (CAS 428823-80-7)
- 2,3-Diphenyl-1,4-dihydrochromeno[4,3-b]pyrrole (CAS 88989-41-7)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
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