4-(2,2,2-Trifluoroethyl)azetidin-2-one CAS 1354963-56-6
| CAS No. | 1354963-56-6 |
| Molecular Formula | C5H6F3NO |
| Molecular Weight | 153.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(2,2,2-Trifluoroethyl)azetidin-2-one is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-(2,2,2-Trifluoroethyl)azetidin-2-one (CAS 1354963-56-6) is a high-purity analytical reference standard with the molecular formula C5H6F3NO and a molecular weight of 153.10 g/mol.
Owing to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(2,2,2-Trifluoroethyl)azetidin-2-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 153.10 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2,2,2-Trifluoroethyl)azetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6F3NO |
| Molecular Weight | 153.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoroethyl Standards
- n-(2,2,2-Trifluoroethyl)cyclobutanamine (CAS 1116744-54-7)
- 3-(2,2,2-Trifluoroethyl)pyrrolidine (CAS 1269400-69-2)
- 1-(2,2,2-Trifluoroethyl)pyrrolidine (CAS 1378304-83-6)
- (R)-3-(2,2,2-trifluoroethyl)pyrrolidine (CAS 1430091-56-7)
- (S)-3-(2,2,2-trifluoroethyl)pyrrolidine (CAS 1430091-57-8)
- N-(2,2,2-Trifluoroethyl)azetidin-3-amine (CAS 1332886-61-9)
- 1-(2,2,2-Trifluoroethyl)azetidin-3-amine (CAS 1339236-05-3)
- 3-(2,2,2-Trifluoroethyl)-2,5-dihydro-1H-pyrrole (CAS 1895856-54-8)
Recommended Standards
- (R)-5-(Trifluoromethyl)pyrrolidin-2-one (CAS 1311255-07-8)
- 5-(Trifluoromethyl)pyrrolidin-2-one (CAS 141519-28-0)
- (5S)-5-(trifluoromethyl)pyrrolidin-2-one (CAS 1287211-10-2)
- 5-methyl-1,2,4-oxadiazole-3-carbonyl azide (CAS 1423029-02-0)
- (1R,2R)-2-(2,3-dimethylbenzoyl)cyclopentane-1-carboxylic acid (CAS 733741-12-3)
- 3-Bromo-7-fluoro-1H-pyrrolo[3,2-c]pyridine (CAS 1190320-09-2)
- Anthracene-9-thiol (CAS 17534-14-4)
- (8-(3,4-Dimethoxyphenyl)-1,4-dioxaspiro[4.5]Decan-8-yl)methanamine (CAS 887978-91-8)
- 6-(2-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 478043-63-9)
- 2-(3-Isopropyl-4-methoxyphenyl)acetaldehyde (CAS 134435-50-0)
- (Z)-N'-(4-Chlorophenyl)-N,N-dimethylmethanimidamide (CAS 74739-49-4)
- Sertraline Impurity 76 (CAS CATO-C4X-134476)
- 2-tert-butylcyclohexan-1-one (CAS 1728-46-7)
- Prolactin-Releasing Peptide (1-31) (human) (CAS 215510-22-8)
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