Sertraline Impurity 76 CAS CATO-C4X-134476
| CAS No. | CATO-C4X-134476 |
| Molecular Formula | C17H17ClN2O |
| Molecular Weight | 300.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Sertraline Impurity 76 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Sertraline Impurity 76 (CAS CATO-C4X-134476), a pharmacopoeial impurity reference standard (molecular formula C17H17ClN2O, MW 300.78 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Sertraline Impurity 76 (C17H17ClN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 300.78 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H17ClN2O |
| Molecular Weight | 300.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Sertraline Standards
- Sertraline Impurity 72 (CAS CATO-C4X-134472)
- Sertraline Impurity 73 (CAS CATO-C4X-134473)
- Sertraline Impurity 77 (CAS CATO-C4X-134477)
- Sertraline Impurity 68 (CAS CATO-C4X-134468)
- Sertraline Impurity 51 (CAS CATO-C4X-134451)
- Sertraline Impurity 64 (CAS 79560-20-6)
- Sertraline oxime Impurity (CAS 152642-35-8)
- Sertraline Impurity C49 (CAS 140631-53-4)
Recommended Standards
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- Tadalafil Impurity 171 (CAS CATO-C4X-1087171)
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- tert-Butyl (2-hydroxyethyl)(isopropyl)carbamate (CAS 610309-73-4)
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