6-(2-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one CAS 478043-63-9
| CAS No. | 478043-63-9 |
| Molecular Formula | C18H9Cl2F3N2O2 |
| Molecular Weight | 413.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-(2-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one.
CATO supplies 6-(2-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 478043-63-9), a certified reference material (molecular formula C18H9Cl2F3N2O2, MW 413.18 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 6-(2-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 413.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(2-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H9Cl2F3N2O2 |
| Molecular Weight | 413.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzoyl Standards
- 6-(3-Chlorobenzoyl)-2-(2-chlorophenyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one (CAS 478043-62-8)
- 6-(4-Chlorobenzoyl)-2-(2-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 478043-58-2)
- 6-(4-Chlorobenzoyl)-2-(3-chlorophenyl)-5-(trifluoromethyl)pyridazin-3(2H)-one (CAS 478043-59-3)
- 6-(4-Chlorobenzoyl)-2-(4-chlorophenyl)-5-(trifluoromethyl)-2,3-dihydropyridazin-3-one (CAS 478043-60-6)
- 2-(4-Chlorobenzoyl)-3-{[(2-chlorophenyl)sulfanyl]methyl}-1-benzofuran (CAS 338424-02-5)
- 2-(4-Chlorobenzoyl)-3-{[(4-chlorophenyl)sulfanyl]methyl}-1-benzofuran (CAS 338411-44-2)
- 1-Benzyl-2-[1-(4-chlorobenzoyl)-1H-pyrazol-3-yl]-1H-1,3-benzodiazole (CAS 477711-18-5)
- 1-(3-Chlorobenzoyl)-4-{[3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidine (CAS 1775471-63-0)
Recommended Standards
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