Bosentan Impurity 14 CAS 1355251-10-3
| CAS No. | 1355251-10-3 |
| Molecular Formula | C20H27NO4S2 |
| Molecular Weight | 409.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bosentan Impurity 14 (CAS 1355251-10-3) is a certified pharmaceutical impurity reference standard with the molecular formula C20H27NO4S2 and a molecular weight of 409.56 g/mol.
The molecular framework of Bosentan Impurity 14 (C20H27NO4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bosentan Impurity 14 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H27NO4S2 |
| Molecular Weight | 409.56 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Bosentan Standards
- Bosentan Impurity 13 (CAS CATO-C4X-156413)
- Bosentan Impurity 23 (CAS CATO-C4X-156423)
- Bosentan USP Related Compound D (CAS 150728-13-5)
- Bosentan Impurity 22 (CAS CATO-C4X-156422)
- Bosentan Impurity N8 (CAS 329923-15-1)
- Bosentan Impurity 8 (CAS 150728-12-4)
- Bosentan USP Related Compound B (CAS 174227-14-6)
- Bosentan USP Related Compound A (CAS 150727-06-3)
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Why CATO?
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