3-(6-Fluoropyridin-2-yl)-5-nitro-1H-indazole CAS 1356087-86-9
| CAS No. | 1356087-86-9 |
| Molecular Formula | C12H7FN4O2 |
| Molecular Weight | 258.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-(6-Fluoropyridin-2-yl)-5-nitro-1H-indazole (CAS 1356087-86-9) is a high-purity analytical reference standard with the molecular formula C12H7FN4O2 and a molecular weight of 258.21 g/mol.
The molecular framework of 3-(6-Fluoropyridin-2-yl)-5-nitro-1H-indazole (C12H7FN4O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7FN4O2 |
| Molecular Weight | 258.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Fluoropyridin Standards
- 3-(5-Fluoropyridin-2-yl)-5-nitro-1H-indazole (CAS 1356087-90-5)
- 4-(4-(6-Fluoropyridin-3-yl)phenyl)morpholine (CAS 1571072-90-6)
- Methyl 4-(3-fluoropyridin-4-yl)-3-formylbenzoate (CAS 1643978-45-3)
- N'-(6-Fluoropyridin-2-yl)-4-methoxybenzohydrazide (CAS 338780-90-8)
- 1-(6-Fluoropyridin-2-yl)-4-phenyl-1H-pyrazol-3-amine (CAS 318284-43-4)
- 4-(6-Fluoropyridin-3-yl)-6-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile (CAS 2222654-09-1)
- Ethyl 1-(5-fluoropyridin-2-yl)piperidine-4-carboxylate (CAS 1310820-59-7)
- 3-(6-Fluoropyridin-2-yl)-7,12-dioxa-3-azaspiro[5.6]Dodec-9-ene (CAS 339110-50-8)
Recommended Standards
- 5-(4-fluorophenyl)[1,2,4]triazolo[1,5-a]pyrimidine-7-carboxylic acid (CAS 1018143-24-2)
- Memantine Impurity 64 (CAS 2123482-13-1)
- 2-(2-Amino-5-(pentafluoro-λ6-sulfanyl)phenyl)acetonitrile (CAS 1379811-93-4)
- N1-(4-(Trifluoromethyl)phenyl)fumaramide (CAS 367908-32-5)
- Ethyl 2-(pyrimidin-2-yl)propanoate (CAS 191725-65-2)
- (R)-1-(4-Chloro-5-methylpyrimidin-2-yl)pyrrolidin-3-ol (CAS 1389320-31-3)
- Sudan I-d5 (CAS 752211-63-5)
- Avanafil Impurity 19 (CAS 2250242-12-5)
- 5-Bromo-2-(1H-pyrazol-4-yl)aniline (CAS 1820683-34-8)
- Neu5Gcα(2-6)Galβ MP Glycoside (CAS 1072896-38-8)
- 2-Methylbutyl 4-methylbenzenesulfonate (CAS 63526-71-6)
- tert-Butyl 2-(4-methylbenzyl)hydrazinecarboxylate (CAS 162739-90-4)
- Ethyl 6-fluoroquinoline-8-carboxylate (CAS 1822817-83-3)
- Exenatide (CAS 141758-74-9)
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