4-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine CAS 1357947-04-6
| CAS No. | 1357947-04-6 |
| Molecular Formula | C6H3BrIN3 |
| Molecular Weight | 323.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine is closely related to a nitrile group, bromine/iodine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine (CAS 1357947-04-6), molecular formula C6H3BrIN3 and molecular weight 323.92 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine (C6H3BrIN3) is characterized by a nitrile group, bromine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H3BrIN3 |
| Molecular Weight | 323.92 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br/I-containing |
| Nitrogen Atoms | 3 |
Related Bromo Standards
- 6-Bromo-3-iodo-imidazo[1,2-a]pyrazine (CAS 1245644-42-1)
- 8-Bromo-3-iodoimidazo[1,2-α]pyrazine (CAS 1245644-46-5)
- 3-Bromo-5-iodo-2H-pyrazolo[3,4-b]pyridine (CAS 1305324-61-1)
- 6-Bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine (CAS 1357945-49-3)
- 7-Bromo-3-iodo-1H-pyrazolo[3,4-c]pyridine (CAS 1357946-18-9)
- 5-bromo-3-iodo-1H-pyrazolo[4,3-b]pyridine (CAS 1357946-54-3)
- 6-Bromo-3-iodo-1H-pyrazolo[3,4-b]pyridine (CAS 1357946-55-4)
- 4-Bromo-3-iodo-1H-pyrazolo[4,3-c]pyridine (CAS 1357946-69-0)
Recommended Standards
- 4-Bromo-3-iodo-2H-pyrazolo[3,4-c]pyridine (CAS 1357946-92-9)
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