Betahistine Impurity 13 HCl CAS 13585-92-7（free base）

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.13585-92-7（free base）
Molecular FormulaC8H12N2O
Molecular WeightN/A
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Betahistine Impurity 13 HCl CAS 13585-92-7（free base） chemical structure

Description

Compared with other compounds in its class, the molecular weight of 188.66 g/mol gives Betahistine Impurity 13 HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Betahistine Impurity 13 HCl (CAS 13585-92-7（free base）) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N2OHCl and a molecular weight of 188.66 g/mol.

The molecular framework of Betahistine Impurity 13 HCl (C8H12N2OHCl) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H12N2O HCl
Molecular Weight188.66 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Halogen ContentCl-containing
Nitrogen Atoms2

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