Carbidopa EP Impurity H CAS 1361017-74-4
| CAS No. | 1361017-74-4 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 240.26 g/mol gives Carbidopa EP Impurity H distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Carbidopa EP Impurity H (CAS 1361017-74-4) is a certified pharmaceutical impurity reference standard with the molecular formula C11H16N2O4 and a molecular weight of 240.26 g/mol.
The molecular framework of Carbidopa EP Impurity H (C11H16N2O4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Carbidopa EP Impurity H meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Carbidopa Standards
- rac-Carbidopa EP Impurity C (CAS 85933-19-3)
- Carbidopa Impurity 11 (CAS CATO-C4X-231011)
- Carbidopa Impurity 29 (CAS CATO-C4X-231029)
- Carbidopa EP Impurity C (CAS 84488-77-7)
- Carbidopa impurity 38 (CAS 2470439-16-6)
- Carbidopa EP Impurity E (CAS 52514-63-3)
- Carbidopa impurity 39 (CAS 2354546-08-8)
- Carbidopa impurity 40 (CAS CATO-C4X-231040)
Recommended Standards
- Isoprenaline Impurity 20 (CAS CATO-C4X-277520)
- Isoprenaline impurity 21 (CAS CATO-C4X-277521)
- N-Nitroso Isoprenaline Impurity 35 (CAS CATO-C4X-277535)
- 2-((3-Hydroxybenzylidene)amino)benzamide (CAS 107618-45-1)
- Rosuvastatin Impurity 226 (CAS CATO-C4X-1169226)
- Desloratadine EP Impurity B(DiHCl) (CAS 183198-49-4（free base）)
- Vortioxetine Impurity 122 (CAS 2831955-36-1)
- Methyl 2,3-O-(1-Methylethylidene)-α-D-lyxopyranoside (CAS 60562-98-3)
- 2-(4-Hydrazinylphenyl)-2-methylpropanenitrile (CAS 1359703-30-2)
- 5-(4-Ethoxyphenyl)nicotinic acid (CAS 1048307-98-7)
- N-(p-Toluenesulfonyl)-L-phenylalanine (CAS 13505-32-3)
- n-((3-Methyl-1h-pyrazol-4-yl)methyl)pentan-1-amine (CAS 1156720-60-3)
- 5,6-Dichloropyrimidine-4-carboxylic acid (CAS 914916-97-5)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
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