Carbidopa EP Impurity C CAS 84488-77-7
| CAS No. | 84488-77-7 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Carbidopa EP Impurity C (CAS 84488-77-7, C11H16N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Carbidopa EP Impurity C (C11H16N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 240.26 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 2 |
Related Carbidopa Standards
- rac-Carbidopa EP Impurity C (CAS 85933-19-3)
- Carbidopa Impurity 11 (CAS CATO-C4X-231011)
- Carbidopa Impurity 29 (CAS CATO-C4X-231029)
- Carbidopa impurity 38 (CAS 2470439-16-6)
- Carbidopa EP Impurity E (CAS 52514-63-3)
- Carbidopa EP Impurity H (CAS 1361017-74-4)
- Carbidopa impurity 39 (CAS 2354546-08-8)
- Carbidopa impurity 40 (CAS CATO-C4X-231040)
Recommended Standards
- Racemic carbidopa methyl ester (CAS 91431-01-5)
- Varenicline Impurity 44 (CAS CATO-C4X-196244)
- Isoprenaline Impurity 20 (CAS CATO-C4X-277520)
- Varenicline Impurity 13 (CAS 2755871-02-2)
- Lincomycin Impurity 17 (CAS CATO-C4X-134217)
- Ketoprofen EP Impurity H (CAS 5689-33-8)
- Azithromycin EP Impurity N (CAS 612069-25-7)
- 8-Chloro-11-(2-fluorophenyl)-3,3-dimethyl-2,3,4,5,10,11-hexahydro-1H-dibenzo[b,e][1,4]diazepin-1-one (CAS 1020252-52-1)
- n-Hexylbicyclo[2.2.1]heptan-2-amine (CAS 1249827-61-9)
- 1-Phenyloctahydropyrrolo[3,4-b]pyrrole (CAS 128758-05-4)
- n-Cyclobutyl-2-methylcyclohexan-1-amine (CAS 1251358-57-2)
- (2-((1-Cyclopropylethyl)amino)phenyl)methanol (CAS 1157627-78-5)
- 2-Chloro-3-ethyl-6,8-dimethylquinoline (CAS 606091-79-6)
- Semaglutide impurity 95 (CAS CATO-C4X-222695)
Why CATO?
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