Carbidopa EP Impurity E CAS 52514-63-3
| CAS No. | 52514-63-3 |
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Carbidopa EP Impurity E (C11H16N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Carbidopa EP Impurity E (CAS 52514-63-3) is a certified pharmaceutical impurity reference standard with the molecular formula C11H16N2O4 and a molecular weight of 240.26 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Carbidopa EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O4 |
| Molecular Weight | 240.26 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 2 |
Related Carbidopa Standards
- rac-Carbidopa EP Impurity C (CAS 85933-19-3)
- Carbidopa Impurity 11 (CAS CATO-C4X-231011)
- Carbidopa Impurity 29 (CAS CATO-C4X-231029)
- Carbidopa EP Impurity C (CAS 84488-77-7)
- Carbidopa impurity 38 (CAS 2470439-16-6)
- Carbidopa EP Impurity H (CAS 1361017-74-4)
- Carbidopa impurity 39 (CAS 2354546-08-8)
- Carbidopa impurity 40 (CAS CATO-C4X-231040)
Recommended Standards
- Isoprenaline Impurity 20 (CAS CATO-C4X-277520)
- Isoprenaline impurity 21 (CAS CATO-C4X-277521)
- Racemic carbidopa methyl ester (CAS 91431-01-5)
- N-Nitroso Isoprenaline Impurity 35 (CAS CATO-C4X-277535)
- Relugolix Impurity 159 (CAS CATO-C4X-2429159)
- Oseltamivir Impurity 53 (CAS 204255-11-8 (unlabelled))
- Estriol Impurity 21 (CAS CATO-C4X-163721)
- Pelrinone (CAS 94386-65-9)
- 3-(4-Methylpiperazinomethyl)-4-thiomethylbenzophenone (CAS 898788-56-2)
- 3-BROMO-N-(1-HYDROXY-2-METHYLPROPAN-2-YL)BENZAMIDE (CAS 211388-38-4)
- 2-(4-Chloro-5-methyl-1H-pyrazol-1-yl)propanamide (CAS 1172960-86-9)
- Iron(III) ethoxide (CAS 5058-42-4)
- 4-[(3,5-Dimethyl-1,2-oxazol-4-yl)methyl]morpholine (CAS 173850-36-7)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
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