Amphotericin B Impurity 30 CAS 136135-61-0
| CAS No. | 136135-61-0 |
| Molecular Formula | C49H77NO18 |
| Molecular Weight | 968.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C49H77NO18, Amphotericin B Impurity 30 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 968.13 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Amphotericin B Impurity 30 (CAS 136135-61-0), a pharmacopoeial impurity reference standard (molecular formula C49H77NO18, MW 968.13 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Amphotericin B Impurity 30 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C49H77NO18 |
| Molecular Weight | 968.13 g/mol |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Nitrogen Atoms | 1 |
Related Amphotericin Standards
- Amphotericin B Impurity 2(N-Acetyl Amphotericin B) (CAS 902457-23-2)
- Amphotericin B Ethyl Ester (CAS 55298-62-9)
- Amphotericin B Impurity 27 (CAS CATO-C4X-184427)
- Amphotericin B EP Impurity C (CAS CATO-C4X-18444)
- Amphotericin B ChP Impurity E (CAS CATO-C4X-184414)
- Amphotericin B Impurity 28 (CAS CATO-C4X-184428)
- Amphotericin B Impurity 8 (CAS CATO-C4X-18448)
- Amphotericin Impurity 9 (CAS CATO-C4X-18449)
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