阿福特罗杂质 CAS 1361398-65-3
| CAS No. | 1361398-65-3 |
| Molecular Formula | C16H16BrNO3 |
| Molecular Weight | 350.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 350.21 g/mol gives 阿福特罗杂质 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
阿福特罗杂质 (CAS 1361398-65-3) is a certified pharmaceutical impurity reference standard with the molecular formula C16H16BrNO3 and a molecular weight of 350.21 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution, 阿福特罗杂质 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 350.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), 阿福特罗杂质 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H16BrNO3 |
| Molecular Weight | 350.21 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- N-(4-Bromophenyl)-5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine (CAS 827580-60-9)
- Formoterol Impurity 28 (CAS 201677-59-0)
- N-(3-Bromophenyl)-2-(4-methoxyphenoxy)propanamide (CAS 302806-81-1)
- Formoterol Impurity 59 (CAS 306966-56-3)
- Osimertinib Impurity 101 (CAS CATO-C4X-2045101)
- Ivermectin EP Impurity I(Mixture of Diastereomers) (CAS 1135339-49-9)
- Lefamulinum Impurity 17 (CAS CATO-C4X-304717)
- 1-(4-Chlorobenzyl)-6-cyclopropyl-3-methyl-1h-pyrazolo[3,4-b]pyridine-4-carbohydrazide (CAS 938006-75-8)
- (R)-1-(4-Bromophenyl)-3-methylbutan-1-amine hydrochloride (CAS 2241594-10-3)
- Pyridine-2-aldoxime (CAS 873-69-8)
- 4744-08-5 1,1-Diethoxypropane Propane, 1,1-diethoxy- Propionaldehyde, diethyl acetal (8CI) Diethyl propional EINECS 225-257-8 NSC 227930 Propanal diethyl acetal Propanaldiethylacetal Propionaldehyde diethyl acetal (CAS 4744-08-5)
- 5-Bromo-N-butylpyrimidin-2-amine (CAS 14001-71-9)
- Regorafenib EP Impurity A (CAS 757251-39-1)
- Exenatide (CAS 141758-74-9)
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