Fluocinolone Acetonide EP Impurity J CAS 1361531-95-4
| CAS No. | 1361531-95-4 |
| Molecular Formula | C24H30F2O6 |
| Molecular Weight | 452.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Fluocinolone Acetonide EP Impurity J (CAS 1361531-95-4, C24H30F2O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Fluocinolone Acetonide EP Impurity J is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 452.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fluocinolone Acetonide EP Impurity J under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H30F2O6 |
| Molecular Weight | 452.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide EP Impurity K (CAS CATO-C4X-238111)
- Fluocinolone Acetonide (CAS 67-73-2)
- Fluocinolone Acetonide Impurity 38 (CAS CATO-C4X-238138)
- Fluocinolone Acetonide Impurity 41 (CAS CATO-C4X-238141)
- Fluocinolone Acetonide Impurity 3 (CAS 4306-83-6)
- Fluocinolone Acetonide Impurity 40 (CAS CATO-C4X-238140)
- Fluocinolone Acetonide Impurity 31 (CAS 1178-54-7)
- Fluocinolone Acetonide Impurity 16 (CAS CATO-C4X-238116)
Recommended Standards
- Flumethasone Impurity 5 (CAS CATO-C4X-19105)
- Flumethasone Impurity 4 (CAS CATO-C4X-19104)
- Diflorasone impurity 4 (CAS CATO-C4X-24804)
- Flumethasone Impurity 3 (CAS CATO-C4X-19103)
- Clomipramine EP Impurity C (CAS 2095-42-3)
- Relugolix Impurity 72 (CAS CATO-C4X-242972)
- Regorafenib Impurity 54 (CAS 6843-37-4)
- 4-Bromo-2-(2,2,2-trifluoroethoxy)benzaldehyde (CAS 1099630-09-7)
- N-(3-chlorophenyl)-1,4-diazepane-1-carboxamide (CAS 815651-24-2)
- Phloroglucinol Impurity 40 (CAS CATO-C4X-221740)
- (R)-(5-Phenyl-4,5-dihydroisoxazol-5-yl)methanol (CAS 842163-69-3)
- 2-Cyclopropyl-6-methylisonicotinic acid (CAS 1256805-64-7)
- (2H-1,2,3-Triazol-4-yl)methanol (CAS 1012040-38-8)
- CBP501 Affinity Peptide trifluoroacetate salt (CAS 1351804-17-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com