Fluocinolone Acetonide CAS 67-73-2
| CAS No. | 67-73-2 |
| Molecular Formula | C24H30F2O6 |
| Molecular Weight | 452.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 452.49 g/mol gives Fluocinolone Acetonide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Fluocinolone Acetonide (CAS 67-73-2), a certified reference material (molecular formula C24H30F2O6, MW 452.49 g/mol) for analytical method development and quality control.
The molecular framework of Fluocinolone Acetonide (C24H30F2O6) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H30F2O6 |
| Molecular Weight | 452.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
Related Fluocinolone Standards
- Fluocinolone Acetonide EP Impurity J (CAS 1361531-95-4)
- Fluocinolone Acetonide EP Impurity K (CAS CATO-C4X-238111)
- Fluocinolone Acetonide Impurity 38 (CAS CATO-C4X-238138)
- Fluocinolone Acetonide Impurity 41 (CAS CATO-C4X-238141)
- Fluocinolone Acetonide Impurity 3 (CAS 4306-83-6)
- Fluocinolone Acetonide Impurity 40 (CAS CATO-C4X-238140)
- Fluocinolone Acetonide Impurity 31 (CAS 1178-54-7)
- Fluocinolone Acetonide Impurity 16 (CAS CATO-C4X-238116)
Recommended Standards
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com