2-(Aminomethyl)-5-(difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine CAS 1361699-76-4
| CAS No. | 1361699-76-4 |
| Molecular Formula | C9H9F5N2O |
| Molecular Weight | 256.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Aminomethyl)-5-(difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine (CAS 1361699-76-4), molecular formula C9H9F5N2O and molecular weight 256.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Aminomethyl)-5-(difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine (C9H9F5N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Aminomethyl)-5-(difluoromethyl)-6-methoxy-3-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9F5N2O |
| Molecular Weight | 256.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Aminomethyl Standards
- (4-(Aminomethyl)-5-(difluoromethyl)-6-(trifluoromethyl)pyridin-3-yl)methanol (CAS 1361465-01-1)
- 2-(Aminomethyl)-3-(difluoromethyl)-5-methoxy-4-(trifluoromethyl)pyridine (CAS 1361468-48-5)
- 2-(Aminomethyl)-5-(difluoromethyl)-3-(trifluoromethyl)pyridine-6-methanol (CAS 1361698-88-5)
- 2-(Aminomethyl)-4-(difluoromethyl)-5-(trifluoromethyl)pyridine-3-methanol (CAS 1361700-69-7)
- 2-(Aminomethyl)-3-(difluoromethyl)-4-(trifluoromethyl)pyridine-6-methanol (CAS 1361732-88-8)
- (4-(Aminomethyl)-5-(difluoromethyl)-6-(trifluoromethyl)pyridin-2-yl)methanol (CAS 1361733-18-7)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-(trifluoromethyl)pyridine-4-methanol (CAS 1361763-53-2)
- 2-(Aminomethyl)-6-(difluoromethyl)-3-methoxy-5-(trifluoromethyl)pyridine (CAS 1361771-18-7)
Recommended Standards
- Methyl 2-cyano-2-(2,3-difluoro-6-nitrophenyl)acetate (CAS 2055119-07-6)
- Butoxytriethoxytitanium (CAS 93918-91-3)
- 8-fluoro-6-(3,3,3-trifluoroprop-1-ynyl)-1H-quinazolin-4-one (CAS 2515616-27-8)
- 2-(Aminomethyl)-4-(difluoromethyl)-3-methoxy-5-(trifluoromethyl)pyridine (CAS 1361787-05-4)
- 2-(2-(Benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acid (CAS 313240-26-5)
- 5-Fluoro-2-(pentyloxy)benzaldehyde (CAS 1096331-34-8)
- 3-(3-Aminopropoxy)benzoic acid (CAS 1341074-73-4)
- 9-Methyl-4-oxo-2-thiomorpholino-4H-pyrido[1,2-a]pyrimidine-3-carbaldehyde (CAS 489401-12-9)
- 6-Bromo-3-(3-chlorophenyl)-[1,2,4]triazolo[4,3-a]pyridine (CAS 1418143-39-1)
- Bolfortan (CAS 668-56-4)
- 3-(Anthracene-9-carbonyl)quinolin-4(1H)-one (CAS 821004-13-1)
- 3-Methoxy-3-(trifluoromethyl)azetidine hydrochloride (CAS 2126162-29-4)
- 8-Fluoro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine (CAS 616201-87-7)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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