Azilsartan Impurity 80 CAS 136285-66-0
| CAS No. | 136285-66-0 |
| Molecular Formula | C10H8ClNO5 |
| Molecular Weight | 257.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Azilsartan Impurity 80 (C10H8ClNO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 257.63 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Azilsartan Impurity 80 (CAS 136285-66-0) is a certified pharmaceutical impurity reference standard with the molecular formula C10H8ClNO5 and a molecular weight of 257.63 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Azilsartan Impurity 80 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO5 |
| Molecular Weight | 257.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Azilsartan Standards
- Azilsartan Impurity 114 (CAS CATO-C4X-1096114)
- Azilsartan Impurity 61 (CAS 856414-36-3)
- Azilsartan Impurity 66 (CAS CATO-C4X-109666)
- Azilsartan Impurity 90 (CAS 73833-13-3)
- Azilsartan Impurity 75 (CAS 2826360-62-5)
- Azilsartan Impurity 76 (CAS CATO-C4X-109676)
- Azilsartan Impurity 77 (CAS CATO-C4X-109677)
- Azilsartan Impurity 37 (CAS 80841-79-8)
Recommended Standards
- n'-(2-Chloroacetyl)-4-nitrobenzohydrazide (CAS 50677-28-6)
- 3-Chloro-4-(difluoromethoxy)benzenesulfonamide (CAS 1152860-14-4)
- n'-(2-Chloroacetyl)-3-nitrobenzohydrazide (CAS 63002-52-8)
- 2-Chloro-3-phenyl-5-(trifluoromethyl)pyridine (CAS 1214341-78-2)
- Cabazitaxel Impurity 14 (CAS CATO-C4X-111514)
- Labetalol Impurity 53 (CAS 802620-01-5)
- Urapidil Impurity 20 (CAS CATO-C4X-192420)
- 2,2,2-Trifluoro-N-(3-phenylpropyl)acetamide (CAS 77970-72-0)
- Atracurium EP Impurity A (CAS 87046-74-0)
- 4-Chloro-5'-phenyl-1,1':3',1''-terphenyl (CAS 116941-51-6)
- Alantolactone (CAS 546-43-0)
- 5-Bromo-2-chloro-1-nitro-3-(trifluoromethyl)benzene (CAS 105172-74-5)
- 3-(1-Cyclopropyl-2,5-dimethyl-1H-pyrrol-3-yl)-3-oxopropanenitrile (CAS 1403565-53-6)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com