Azilsartan Impurity 37 CAS 80841-79-8
| CAS No. | 80841-79-8 |
| Molecular Formula | C5H5IO3 |
| Molecular Weight | 240.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Azilsartan Impurity 37 (CAS 80841-79-8) is a certified pharmaceutical impurity reference standard with the molecular formula C5H5IO3 and a molecular weight of 240.00 g/mol.
Azilsartan Impurity 37 (C5H5IO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C5H5IO3 |
| Molecular Weight | 240.00 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | I-containing |
Related Azilsartan Standards
- Azilsartan Impurity 75 (CAS 2826360-62-5)
- Azilsartan Impurity 76 (CAS CATO-C4X-109676)
- Azilsartan Impurity 77 (CAS CATO-C4X-109677)
- Azilsartan Impurity 90 (CAS 73833-13-3)
- Azilsartan Impurity 61 (CAS 856414-36-3)
- Azilsartan Impurity 72 (CAS 21606-04-2)
- Azilsartan Impurity 114 (CAS CATO-C4X-1096114)
- Azilsartan Impurity 80 (CAS 136285-66-0)
Recommended Standards
- 1,5-Dibromopentane-d10 (CAS 1219802-90-0)
- 2,6-Dichloro-3-(trifluoromethyl)benzonitrile (CAS 1092461-02-3)
- 6-Iodouracil (CAS 4269-94-7)
- Cadmium telluride (CAS 1306-25-8)
- Oxcarbazepine Impurity 29 (CAS CATO-C4X-116429)
- Eltrombopag Impurity 127 (CAS CATO-C4X-1198127)
- Bortezomib Impurity 13 (CAS 1446194-56-4)
- Ribociclib impurity 39 (CAS 2304957-86-4)
- 2,3-Dichloro-6-(trifluoromethyl)pyridine (CAS 89719-90-4)
- (2E)-2-[(Ethylamino)methylidene]-4,4-dimethyl-3-oxopentanenitrile (CAS 866152-36-5)
- Pazopanib Impurity 60 (CAS CATO-C4X-172560)
- 2-[2-(4-Cyclohexyl-4H-[1,2,4]triazol-3-yl)-vinyl]-6-methoxy-benzoic acid methyl ester (CAS 365542-72-9)
- Methanesulfonamide, N-[2-fluoro-4-(isothiocyanatomethyl)phenyl]- (CAS 565448-37-5)
- Insulin Degludec Impurity 7 (CAS CATO-C4X-21577)
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