Azilsartan Impurity 90 CAS 73833-13-3
| CAS No. | 73833-13-3 |
| Molecular Formula | C9H6ClNO5 |
| Molecular Weight | 243.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Azilsartan Impurity 90 (CAS 73833-13-3, C9H6ClNO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C9H6ClNO5, Azilsartan Impurity 90 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.60 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Azilsartan Impurity 90 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNO5 |
| Molecular Weight | 243.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1978 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Azilsartan Standards
- Azilsartan Impurity 75 (CAS 2826360-62-5)
- Azilsartan Impurity 76 (CAS CATO-C4X-109676)
- Azilsartan Impurity 77 (CAS CATO-C4X-109677)
- Azilsartan Impurity 37 (CAS 80841-79-8)
- Azilsartan Impurity 61 (CAS 856414-36-3)
- Azilsartan Impurity 114 (CAS CATO-C4X-1096114)
- Azilsartan Impurity 80 (CAS 136285-66-0)
- Azilsartan Impurity 72 (CAS 21606-04-2)
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- (3S)-Hexahydro-3-[(2-methylpropyl)amino]-2H-azepin-2-one (CAS 359782-00-6)
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