1362850-20-1 64CW205BDD Seletalisib [INN] UNII-64CW205BDD Seletalisib Pyrido(3,2-d)pyrimidin-4-amine, N-((1R)-1-(8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl)-2,2,2-trifluoroethyl)- N-((R)-1-(8-Chloro-2-(1-oxopyridin-3-yl)quinolin-3-yl)-2,2,2-trifluoroethyl)pyrido(3,2-d)pyrimidin-4-ylamine 3-(8-Chloro-3-((1R)-1-((pyrido(3,2-d)pyrimidin-4-yl)amino)-2,2,2-trifluoroethyl)quinolin-2-yl)pyridine N-oxide CAS 1362850-20-1

Description

The occurrence of 1362850-20-1 64CW205BDD Seletalisib [INN] UNII-64CW205BDD Seletalisib Pyrido(3,2-d)pyrimidin-4-amine, N-((1R)-1-(8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl)-2,2,2-trifluoroethyl)- N-((R)-1-(8-Chloro-2-(1-oxopyridin-3-yl)quinolin-3-yl)-2,2,2-trifluoroethyl)pyrido(3,2-d)pyrimidin-4-ylamine 3-(8-Chloro-3-((1R)-1-((pyrido(3,2-d)pyrimidin-4-yl)amino)-2,2,2-trifluoroethyl)quinolin-2-yl)pyridine N-oxide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

1362850-20-1 64CW205BDD Seletalisib [INN] UNII-64CW205BDD Seletalisib Pyrido(3,2-d)pyrimidin-4-amine, N-((1R)-1-(8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl)-2,2,2-trifluoroethyl)- N-((R)-1-(8-Chloro-2-(1-oxopyridin-3-yl)quinolin-3-yl)-2,2,2-trifluoroethyl)pyrido(3,2-d)pyrimidin-4-ylamine 3-(8-Chloro-3-((1R)-1-((pyrido(3,2-d)pyrimidin-4-yl)amino)-2,2,2-trifluoroethyl)quinolin-2-yl)pyridine N-oxide (CAS 1362850-20-1) is a high-purity analytical reference standard with the molecular formula C23H14ClF3N6O and a molecular weight of 482.85 g/mol.

The molecular framework of 1362850-20-1 64CW205BDD Seletalisib [INN] UNII-64CW205BDD Seletalisib Pyrido(3,2-d)pyrimidin-4-amine, N-((1R)-1-(8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl)-2,2,2-trifluoroethyl)- N-((R)-1-(8-Chloro-2-(1-oxopyridin-3-yl)quinolin-3-yl)-2,2,2-trifluoroethyl)pyrido(3,2-d)pyrimidin-4-ylamine 3-(8-Chloro-3-((1R)-1-((pyrido(3,2-d)pyrimidin-4-yl)amino)-2,2,2-trifluoroethyl)quinolin-2-yl)pyridine N-oxide (C23H14ClF3N6O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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