Tivozanib Impurity 13 CAS CATO-C4X-340013
| CAS No. | CATO-C4X-340013 |
| Molecular Formula | C23H19ClN4O6 |
| Molecular Weight | 482.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tivozanib Impurity 13 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Tivozanib Impurity 13 (CAS CATO-C4X-340013), a pharmacopoeial impurity reference standard (molecular formula C23H19ClN4O6, MW 482.87 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tivozanib Impurity 13 (C23H19ClN4O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 482.87 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tivozanib Impurity 13 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H19ClN4O6 |
| Molecular Weight | 482.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Tivozanib Standards
- Tivozanib Impurity 20 (CAS CATO-C4X-340020)
- Tivozanib Impurity 10 (CAS CATO-C4X-340010)
- Tivozanib Impurity 14 (CAS CATO-C4X-340014)
- Tivozanib D6 (CAS CATO-C4X-34001)
- Tivozanib (CAS 475108-18-0)
- Tivozanib Impurity 12 (CAS CATO-C4X-340012)
- Tivozanib Impurity 18 (CAS CATO-C4X-340018)
- Tivozanib Impurity 16 (CAS CATO-C4X-340016)
Recommended Standards
- 17a(H),21B(H)-(22RS)-Pentakishomohopane (CAS 54370-82-0)
- N-allyl-6-(((4-chlorophenyl)thio)methyl)-2-((3,4-dichlorobenzyl)thio)pyrimidin-4-amine (CAS 478261-64-2)
- 1362850-20-1 64CW205BDD Seletalisib [INN] UNII-64CW205BDD Seletalisib Pyrido(3,2-d)pyrimidin-4-amine, N-((1R)-1-(8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl)-2,2,2-trifluoroethyl)- N-((R)-1-(8-Chloro-2-(1-oxopyridin-3-yl)quinolin-3-yl)-2,2,2-trifluoroethyl)pyrido(3,2-d)pyrimidin-4-ylamine 3-(8-Chloro-3-((1R)-1-((pyrido(3,2-d)pyrimidin-4-yl)amino)-2,2,2-trifluoroethyl)quinolin-2-yl)pyridine N-oxide (CAS 1362850-20-1)
- 3-((4-Bromobenzyl)thio)-5-(((4-chlorobenzyl)thio)methyl)-4-isopropyl-4H-1,2,4-triazole (CAS 344268-27-5)
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- 2,4,6-Trimethylbenzophenone (CAS 954-16-5)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com