Tiotropium Bromide CAS 136310-93-5
| CAS No. | 136310-93-5 |
| Molecular Formula | C19H22NO4S2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 472.41 g/mol gives Tiotropium Bromide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Tiotropium Bromide (CAS 136310-93-5) is a high-purity analytical reference standard with the molecular formula C19H22NO4S2Br and a molecular weight of 472.41 g/mol.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution, Tiotropium Bromide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 472.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Tiotropium Bromide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H22NO4S2 Br |
| Molecular Weight | 472.41 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Tiotropium Standards
- Tiotropium Impurity 26 (CAS 10299-90-8)
- Tiotropium Bromide Impurity 8 Potassium Salt (CAS 10304-09-3)
- Tiotropium Bromide EP Impurity H (Mixture of Enantiomers) (CAS 1044148-31-3)
- Tiotropium Bromide EP Impurity H-d3 Bromide (Mixture of Enantiomers) (CAS 1044148-31-3（unlabeled）)
- Tiotropium-d6 (CAS 1126775-44-7)
- Tiotropium-D3 Bromide (CAS 1127226-56-5)
- Tiotropium Bromide EP Impurity B (CAS 136310-64-0)
- Tiotropium EP Impurity D (CAS 136310-66-2)
Recommended Standards
- N,N-Dimethyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-4-amine (CAS 2096336-85-3)
- 1-(6,7-Dimethylquinoxalin-2-yl)-3-(3-fluorophenyl)urea (CAS 672950-00-4)
- 3-Iodo-2-isopropoxyphenol (CAS 1243353-32-3)
- 6-Amino-5-bromo-2-(ethylthio)pyrimidin-4(3H)-one (CAS 77708-90-8)
- N-Cyclopentyl-N-methylpyridin-3-amine dihydrochloride (CAS 1185302-30-0)
- 2-(1H-Indol-3-yl)-2-oxo-N-[4-(trifluoromethoxy)phenyl]acetamide (CAS 852367-70-5)
- Thiohempa (CAS 3732-82-9)
- 4'-(Tert-butyl)-[1,1'-biphenyl]-4-carbaldehyde (CAS 221018-01-5)
- 1-Chloro-4-(2-methoxyethoxy)benzene (CAS 60893-72-3)
- Galanin (1-13)-Neuropeptide Y (25-36) amide (CAS 147138-51-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com