Tiotropium Impurity 26 CAS 10299-90-8
| CAS No. | 10299-90-8 |
| Molecular Formula | C9H11Cl |
| Molecular Weight | 154.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Tiotropium Impurity 26 (CAS 10299-90-8, C9H11Cl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to chlorine substitution, an aromatic ring system, Tiotropium Impurity 26 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 154.64 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tiotropium Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11Cl |
| Molecular Weight | 154.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
Related Tiotropium Standards
- Tiotropium impurity N1 (CAS 487-27-4)
- Tiotropium Bromide Impurity 19 (CAS 498-46-4)
- Tiotropium Bromide Impurity 33 (CAS 498-45-3)
- Tiotropium Bromide Impurity 32 (CAS 1570-95-2)
- Tiotropium Impurity 28 (CAS 59516-66-4)
- Tiotropium Impurity 29 (CAS 213967-57-8)
- Tiotropium Bromide Impurity 17 (CAS CATO-C4X-176417)
- Tiotropium Impurity 34 (CAS 169219-67-4)
Recommended Standards
- Alverine EP Impurity A (CAS 104-52-9)
- 1-Chloro-4-methanesulfinylbutane (CAS 53394-81-3)
- Dexmedetomidine Impurity 51 (CAS 13651-55-3)
- 2,2-Dimethylpropane-1-sulfinyl chloride (CAS 82215-38-1)
- Vortioxetine Impurity 3 (CAS 960203-41-2)
- Rivastigmine Impurity 26 (CAS 1213234-40-2)
- Ciclesonide Impurity 15 (CAS 3035286-87-1)
- 2-((4-Bromophenyl)thio)-N-(3,4-dimethylphenyl)acetamide (CAS 329078-45-7)
- 3-Chloro-1-(2,3-dihydro-1h-indol-1-yl)propan-1-one (CAS 64140-62-1)
- (R)-1-Methyl-5-oxopyrrolidine-2-carboxylic acid (CAS 952345-00-5)
- 2-(2-(5,7-Dichlorobenzo[d]oxazol-2-yl)ethyl)isoindoline-1,3-dione (CAS 1071369-46-4)
- N-(4,5-Dihydro-1H-imidazol-2-yl)-5-methyl-6-quinolinamine (CAS 1217439-06-9)
- 4-Iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine (CAS 945600-09-9)
- Gly-Neuroendocrine Regulatory Peptide-3 (human, mouse, rat) trifluoroacetate salt (CAS 1815618-19-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com