Oseltamivir EP Impurity A CAS 1364932-19-3
| CAS No. | 1364932-19-3 |
| Molecular Formula | C14H24N2O4 |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Oseltamivir EP Impurity A.
CATO supplies Oseltamivir EP Impurity A (CAS 1364932-19-3), a pharmacopoeial impurity reference standard (molecular formula C14H24N2O4, MW 284.35 g/mol) used for the identification and quantification of trace impurities in APIs.
Oseltamivir EP Impurity A (C14H24N2O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H24N2O4 |
| Molecular Weight | 284.35 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Oseltamivir Standards
- Oseltamivir EP Impurity C (CAS 187227-45-8)
- Oseltamivir Impurity N42 (CAS 1052063-36-1)
- Oseltamivir Impurity N7 (CAS 1376142-56-1)
- Oseltamivir impurity 203 (CAS CATO-C4X-1720203)
- Oseltamivir Impurity 153 (CAS CATO-C4X-1720153)
- Oseltamivir EP Impurity C-d3 (CAS CATO-C4X-1720233)
- Oseltamivir-d3 Acid (CAS 1242184-43-5)
- Oseltamivir Acid-13CD3 (CAS 187227-45-8 (unlabeled))
Recommended Standards
- Estriol Impurity 17 (CAS CATO-C4X-163717)
- Estradiol Impurity 5 (CAS 1476-34-2)
- Tolterodine Impurity 30 (CAS 124937-62-8)
- Safinamide Impurity 29 (CAS 133865-32-4)
- Itraconazole Impurity 98 (CAS CATO-C4X-149798)
- Ornidazole Impurity 84 (CAS CATO-C4X-133184)
- Emedastine lmpurity 19 (CAS CATO-C4X-226719)
- Quinuclidine-4-thiol hydrobromide (CAS 224296-91-7)
- 4,6-Difluoroindole (CAS 199526-97-1)
- 5-(((2-Chlorobenzyl)thio)methyl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 519045-14-8)
- Methyl 4-chloro-3-hydroxy-5-(phenylthio)thiophene-2-carboxylate (CAS 104386-58-5)
- CAS 2260669-80-3 (CAS 2260669-80-3)
- 1H-Pyrazole-3-carboxamide, 4-[(2,6-dichlorobenzoyl)amino]-N-4-piperidinyl-, (methanesulfonate) (1:1) (CAS 902135-89-1)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com