Estradiol Impurity 5 CAS 1476-34-2
| CAS No. | 1476-34-2 |
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Estradiol Impurity 5 (CAS 1476-34-2) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20O3 and a molecular weight of 284.35 g/mol.
Estradiol Impurity 5 (C18H20O3) contains a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Estradiol Impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Estradiol Standards
- Estradiol Impurity N1 (CAS 4011-48-7)
- Estradiol Impurity 26 (CAS CATO-C4X-163626)
- Estradiol Impurity 27 (CAS CATO-C4X-163627)
- Estradiol Impurity 30 (CAS 4954-08-9)
- Estradiol Impurity 44 (CAS CATO-C4X-163644)
- Estradiol Impurity 51 (CAS 165609-57-4)
- Estradiol Impurity N27 (CAS 15375-21-0)
- Estradiol Impurity 37 (CAS 187024-20-0)
Recommended Standards
- Safinamide Impurity 29 (CAS 133865-32-4)
- Estriol Impurity 17 (CAS CATO-C4X-163717)
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- Oseltamivir EP Impurity A (CAS 1364932-19-3)
- Azilsartan Impurity 50 (CAS 1417576-02-3)
- Brivaracetam Impurity 32 (CAS CATO-C4X-200732)
- Aztreonam impurity 97 (CAS CATO-C4X-152297)
- 4-Chloro-2-isobutyramidobenzoic acid (CAS 405904-57-6)
- Bilastine Impurity 138 (CAS CATO-C4X-2253138)
- 4-(6-((3-Hydroxypropyl)amino)imidazo[1,2-b]pyridazin-3-yl)phenol (CAS 1012344-09-0)
- 3-allylrodanine (CAS 1457-47-2)
- 1-{2-methyl-2,9-diazaspiro[5.5]undecan-9-yl}ethan-1-one (CAS 1824055-90-4)
- Tizanidine impurity 24 (CAS CATO-C4X-144524)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com