Estriol Impurity 17 CAS CATO-C4X-163717
| CAS No. | CATO-C4X-163717 |
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Estriol Impurity 17 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Estriol Impurity 17 (CAS CATO-C4X-163717, C18H20O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C18H20O3, Estriol Impurity 17 contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 284.35 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20O3 |
| Molecular Weight | 284.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Estriol Standards
Recommended Standards
- Estradiol Impurity 5 (CAS 1476-34-2)
- Oseltamivir EP Impurity A (CAS 1364932-19-3)
- Safinamide Impurity 29 (CAS 133865-32-4)
- Oseltamivir EP Impurity C (CAS 187227-45-8)
- Gefitinib Impurity 61 (CAS 950596-57-3)
- Cilastatin EP Impurity A(Mixture Of Diastereomers) (CAS CATO-C4X-19601)
- Bazedoxifene Acetate Impurity 8 (CAS 1802552-31-3)
- 4-Pyrrolidin-3-yl morpholine (CAS 53617-37-1)
- 5-(2,2-Difluorocyclopropyl)pyrimidin-2-amine (CAS 2654054-60-9)
- 4-[3-(2-Methylpropyl)-1,2,4-oxadiazol-5-yl]piperidine (CAS 1042499-82-0)
- 4-Methyl-N-((3-methyloxetan-3-yl)methyl)pentan-1-amine (CAS 1339693-99-0)
- Fmoc-4-fluoro-N-methyl-L-phenylalanine (CAS 1979176-87-8)
- 1-(6-(Diethylamino)pyrimidin-4-yl)piperidine-3-carboxylic acid (CAS 1353946-91-4)
- Tirzepatide Impurity 35 (CAS CATO-C4X-324035)
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