Lemborexant CAS 1369764-02-2
| CAS No. | 1369764-02-2 |
| Molecular Formula | C22H20F2N4O2 |
| Molecular Weight | 410.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Lemborexant is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 410.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Lemborexant (CAS 1369764-02-2), molecular formula C22H20F2N4O2 and molecular weight 410.42 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H20F2N4O2 |
| Molecular Weight | 410.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Lemborexant Standards
- Lemborexant impurity 19 (CAS 2541020-19-1)
- Lemborexant impurity 6 (CAS 3070371-41-1)
- Lemborexant impurity 7 (CAS 3070371-43-3)
- Lemborexant impurity 8 (CAS CATO-C4X-30428)
- Lemborexant Impurity 21 (CAS CATO-C4X-304221)
- Lemborexant Impurity 81 (CAS CATO-C4X-304281)
- Lemborexant Impurity 48 (CAS CATO-C4X-304248)
- Lemborexant Impurity 49 (CAS CATO-C4X-304249)
Recommended Standards
- Fmoc-Dap(Aloc)-OH (CAS 188970-92-5)
- N-[5-[4-[(6-Cyano-3-pyridinyl)methoxy]phenyl][1,2,4]triazolo[1,5-α]pyridin-2-yl]cyclopropanecarboxamide (CAS 1206101-20-3)
- Isepamicin Impurity 7 (CAS CATO-C4X-31117)
- Tris((1H-benzo[d][1,2,3]triazol-1-yl)methyl)amine (CAS 121238-82-2)
- 2-N,2-N-dimethylquinoline-2,6-diamine (CAS 914460-74-5)
- 1-CHloro-4-(octyloxy)benzene (CAS 836-60-2)
- 6-Amino-1,3-benzothiazol-2(3H)-one (CAS 56354-98-4)
- N-(2-Nitrophenyl)acridin-9-amine (CAS 80260-77-1)
- 6-Amino-3-methylisothiazolo[4,5-b]pyrazine-5-carbonitrile (CAS 67209-12-5)
- 4-Hydroxy-5-methyl-2-(pyridin-3-yl)quinoline-3-carbonitrile (CAS 1251033-70-1)
- 4,4,4-Trifluoro-3-hydroxy-3-(trifluoromethyl)butyl methacrylate (CAS 914090-18-9)
- (2S,3S,4S,5S,6R)-2-((4-aminophenyl)thio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 129970-93-0)
- 4-Cyclopropyl-1,2-dimethoxybenzene (CAS 83356-71-2)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
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