Lemborexant impurity 8 CAS CATO-C4X-30428
| CAS No. | CATO-C4X-30428 |
| Molecular Formula | C22H20F2N4O2 |
| Molecular Weight | 410.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lemborexant impurity 8 (CAS CATO-C4X-30428), a pharmacopoeial impurity reference standard (molecular formula C22H20F2N4O2, MW 410.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Lemborexant impurity 8 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 410.42 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Lemborexant impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H20F2N4O2 |
| Molecular Weight | 410.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Lemborexant Standards
- Lemborexant impurity 19 (CAS 2541020-19-1)
- Lemborexant impurity 6 (CAS 3070371-41-1)
- Lemborexant impurity 7 (CAS 3070371-43-3)
- Lemborexant (CAS 1369764-02-2)
- Lemborexant Impurity 21 (CAS CATO-C4X-304221)
- Lemborexant Impurity 81 (CAS CATO-C4X-304281)
- Lemborexant Impurity 48 (CAS CATO-C4X-304248)
- Lemborexant Impurity 49 (CAS CATO-C4X-304249)
Recommended Standards
- Isepamicin Impurity 1 (CAS 118953-87-0)
- Isepamicin Impurity 7 (CAS CATO-C4X-31117)
- Fmoc-Dap(Aloc)-OH (CAS 188970-92-5)
- Abemaciclib Impurity 13 (CAS 1648707-16-7)
- Baclofen Impurity 47 (CAS CATO-C4X-101247)
- Imatinib Impurity 89 (CAS CATO-C4X-106889)
- Salcaprozate Impurity 2 (CAS 1100921-03-6)
- 2-(2,5-Dimethylphenyl)-8-methylquinoline-4-carbonyl chloride (CAS 1160254-19-2)
- Tert-butyl 8-(aminomethyl)-5-thia-2-azaspiro[3.4]Octane-2-carboxylate 5,5-dioxide (CAS 1373029-31-2)
- 3-(2,2-Dimethylpropyl)pyridin-2-amine (CAS 1341706-69-1)
- 5,5'-Methylenebis(2-(benzyloxy)-N,N-dimethylaniline) (CAS 1820608-75-0)
- 1-(4-nitro-2,3-dihydro-1H-indol-1-yl)ethan-1-one (CAS 84807-25-0)
- Ethyl 5-(3-chlorophenyl)-4-iodo-1H-pyrazole-3-carboxylate (CAS 1370022-89-1)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com