Lemborexant Impurity 22 CAS 1369765-96-7
| CAS No. | 1369765-96-7 |
| Molecular Formula | C22H20F2N4O3 |
| Molecular Weight | 426.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Lemborexant Impurity 22 (CAS 1369765-96-7), a pharmacopoeial impurity reference standard (molecular formula C22H20F2N4O3, MW 426.42 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H20F2N4O3, Lemborexant Impurity 22 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H20F2N4O3 |
| Molecular Weight | 426.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Lemborexant Standards
- Lemborexant Impurity 33 (CAS 1369765-94-5)
- Lemborexant Impurity 34 (CAS 1369765-95-6)
- Lemborexant Impurity 35 (CAS CATO-C4X-304235)
- Lemborexant impurity 15 (CAS CATO-C4X-304215)
- Lemborexant Impurity 105 (CAS CATO-C4X-3042105)
- Lemborexant Impurity 31 (CAS CATO-C4X-304231)
- Lemborexant-d6 (CAS CATO-C4X-304267)
- Lemborexant Impurity 21 (CAS CATO-C4X-304221)
Recommended Standards
- Larotrectinib Impurity 16 (CAS 2699151-02-3)
- Tetracycline EP Impurity D (CAS 7518-17-4)
- Tetracycline EP Impurity C (CAS 1665-56-1)
- Azilsartan Impurity 41 (CAS CATO-C4X-109641)
- Nafamostat Impurity 128 (CAS CATO-C4X-1332128)
- Lesinurad Impurity 11 (CAS CATO-C4X-147811)
- Linagliptin Impurity 85 (CAS 6972-82-3)
- (2-Ethoxy-3,4-difluorophenyl)methanol (CAS 2162245-24-9)
- 1,8,15,22-Tetraphenoxy-29H,31H-phthalocyanine (CAS 77474-60-3)
- 3-((Furan-2-ylmethyl)sulfonyl)-1-((4-(trifluoromethoxy)phenyl)sulfonyl)azetidine (CAS 1797020-84-8)
- Ethyl (5-amino-3-((methyl(phenyl)amino)methyl)-1,2-dihydropyrido[3,4-b]pyrazin-7-yl)carbamate (CAS 80434-77-1)
- 2-Phenylpropyl butyrate (CAS 80866-83-7)
- 2-Phenyl-2-[(phenylsulfonyl)amino]butanoic acid (CAS 361464-18-8)
- Calcitonin N-Terminal Flanking Peptide (human) (CAS 118277-01-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com