Lemborexant impurity 02 CAS 1369769-35-6
| CAS No. | 1369769-35-6 |
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lemborexant impurity 02 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lemborexant impurity 02 (CAS 1369769-35-6) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17FN2O3 and a molecular weight of 316.33 g/mol.
Based on its molecular formula C17H17FN2O3, Lemborexant impurity 02 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 316.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lemborexant impurity 02 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Lemborexant Standards
- Lemborexant impurity 5 (CAS 2541020-22-6)
- Lemborexant Impurity 72 (CAS CATO-C4X-304272)
- Lemborexant Impurity 84 (CAS CATO-C4X-304284)
- Lemborexant Impurity 89 (CAS 3070371-44-4)
- Lemborexant Impurity 100 (CAS CATO-C4X-3042100)
- Lemborexant Impurity 44 (CAS CATO-C4X-304244)
- Lemborexant Impurity N1 (CAS 1369767-24-7)
- Lemborexant Impurity 23 (CAS 3037659-15-4)
Recommended Standards
- 4-(5,6-Dimethyl-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)benzoic acid (CAS 1351398-30-5)
- 4-Carbamoyl-2-(4-methoxybenzenesulfonamido)butanoic acid (CAS 1396963-05-5)
- 1-(4-(3-(4-Fluorophenoxy)phenyl)but-3-en-2-yl)-1-hydroxyurea (CAS 134470-38-5)
- 1-Benzosulphonyl-6-methoxy-5-azaindole-2-carbaldehyde (CAS 1427502-93-9)
- Amorolfine impurity 73 (CAS 78613-39-5)
- Fenofibrate Impurity 12 (CAS CATO-C4X-164312)
- Azilsartan impurity 164 (CAS 1948222-11-4)
- 9-Ethyl-8-oxo-6,7,8,9-tetrahydro-5H-carbazole-3-carboxylic acid (CAS 354993-58-1)
- 2,5-Dimethylcyclohexane-1,4-dione (CAS 583-81-3)
- 1-(2-Chloroallyl)-3-fluorobenzene (CAS 731773-03-8)
- Imidocarb Dipropionate (CAS 55750-06-6)
- 1-(4-Chlorophenyl)-5-methyl-1H-pyrazole (CAS 671182-58-4)
- Clemastine Impurity 4 (CAS 20763-27-3)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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