Lemborexant impurity 5 CAS 2541020-22-6
| CAS No. | 2541020-22-6 |
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Lemborexant impurity 5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Lemborexant impurity 5 (CAS 2541020-22-6), a pharmacopoeial impurity reference standard (molecular formula C17H17FN2O3, MW 316.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Lemborexant impurity 5 (C17H17FN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 316.33 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2001 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Lemborexant Standards
- Lemborexant impurity 02 (CAS 1369769-35-6)
- Lemborexant Impurity 72 (CAS CATO-C4X-304272)
- Lemborexant Impurity 84 (CAS CATO-C4X-304284)
- Lemborexant Impurity 89 (CAS 3070371-44-4)
- Lemborexant Impurity 100 (CAS CATO-C4X-3042100)
- Lemborexant Impurity 44 (CAS CATO-C4X-304244)
- Lemborexant Impurity N1 (CAS 1369767-24-7)
- Lemborexant Impurity 23 (CAS 3037659-15-4)
Recommended Standards
- Bimatoprost Impurity 25 (CAS 146964-27-4)
- Safinamide Impurity 46 (CAS 2268802-59-9)
- Safinamide Impurity 4 (CAS CATO-C4X-15904)
- di-tert-butyl (4-(hydroxymethyl)phenyl) phosphate (CAS 857896-79-8)
- Dequalinium EP Impurity C Triiodide (CAS 782426-88-4(free base))
- Methotrexate Impurity 61 (CAS 65148-63-2)
- Celecoxib Impurity 74 (CAS CATO-C4X-104374)
- 5-Chloro-3-fluoro-2-nitropyridine (CAS 1064783-29-4)
- Abemaciclib Impurity 40 (CAS CATO-C4X-293740)
- 79973-42-5 Bis(pentamethylcyclopentadienyl)cobalt(III) hexafluorophosphate Decamethylcobaltocenium hexafluorophosphate (CAS 79973-42-5)
- 1,1-Diethoxy-2-methylbutane (CAS 3658-94-4)
- Isophthalohydrazide (CAS 2760-98-7)
- 2,3-Dimethyl-4-nitrobenzoic acid (CAS 90564-15-1)
- D-Tyr1-Tirzepatide (CAS CATO-CPTD788928)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com