Lemborexant Impurity 72 CAS CATO-C4X-304272
| CAS No. | CATO-C4X-304272 |
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lemborexant Impurity 72.
CATO supplies Lemborexant Impurity 72 (CAS CATO-C4X-304272), a pharmacopoeial impurity reference standard (molecular formula C17H17FN2O3, MW 316.33 g/mol) used for the identification and quantification of trace impurities in APIs.
Lemborexant Impurity 72 (C17H17FN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lemborexant Impurity 72 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H17FN2O3 |
| Molecular Weight | 316.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Lemborexant Standards
- Lemborexant impurity 02 (CAS 1369769-35-6)
- Lemborexant impurity 5 (CAS 2541020-22-6)
- Lemborexant Impurity 84 (CAS CATO-C4X-304284)
- Lemborexant Impurity 89 (CAS 3070371-44-4)
- Lemborexant Impurity 100 (CAS CATO-C4X-3042100)
- Lemborexant Impurity 44 (CAS CATO-C4X-304244)
- Lemborexant Impurity N1 (CAS 1369767-24-7)
- Lemborexant Impurity 23 (CAS 3037659-15-4)
Recommended Standards
- Bimatoprost Impurity 25 (CAS 146964-27-4)
- Safinamide Impurity 46 (CAS 2268802-59-9)
- Ethyl Phenyl(2,4,6-trimethylbenzoyl)phosphinate (CAS 84434-11-7)
- Safinamide Impurity 4 (CAS CATO-C4X-15904)
- Esaxerenone Impurity 7 (CAS 3030872-12-6)
- Febuxostat Impurity 38 (CAS 528607-60-5)
- Fulvestrant Impurity 30 (CAS CATO-C4X-191730)
- tert-Butyl (2-formylimidazo[1,2-a]pyridin-6-yl)carbamate (CAS 2730887-91-7)
- 5-(4-Bromophenyl)-2-(isopropylthio)-1-phenyl-1H-imidazole (CAS 1207020-26-5)
- 3-(2-Bromo-4-nitrophenoxy)pyrrolidine (CAS 1248213-38-8)
- 2-(4-Amino-3-(difluoromethyl)-6-fluoropyridin-2-yl)acetonitrile (CAS 1805063-38-0)
- 2,4-Dibromo-5-(difluoromethyl)nicotinaldehyde (CAS 1804446-28-3)
- 3,5-Dichloro-6-methylpyridin-2-amine (CAS 22137-52-6)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
Why CATO?
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com