1-(5-Chloro-3-fluoropyridin-2-yl)piperazine CAS 1370419-33-2
| CAS No. | 1370419-33-2 |
| Molecular Formula | C9H11ClFN3 |
| Molecular Weight | 215.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Chloro-3-fluoropyridin-2-yl)piperazine (C9H11ClFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1-(5-Chloro-3-fluoropyridin-2-yl)piperazine (CAS 1370419-33-2) is a high-purity analytical reference standard with the molecular formula C9H11ClFN3 and a molecular weight of 215.66 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-(5-Chloro-3-fluoropyridin-2-yl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H11ClFN3 |
| Molecular Weight | 215.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 1-(2-Chloro-5-fluoropyridin-3-yl)piperazine (CAS 1121600-42-7)
- 1-(5-Chloro-2-fluoropyridin-3-yl)piperazine (CAS 1121613-47-5)
- 2-Chloro-N-cyclopentyl-5-fluoropyrimidin-4-amine (CAS 1338495-23-0)
- 3-Chloro-4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxylic acid (CAS 1361003-67-9)
- 4-Chloro-5-methanesulfinyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1389264-16-7)
- 2-chloro-6-methanesulfonylbenzonitrile (CAS 1443981-55-2)
- 5-Chloro-2-(methylsulfonyl)benzonitrile, 97% (CAS 180297-56-7)
- methyl 2-chloro-2H-thieno[3,2-b]pyrrole-5-carboxylate (CAS 1823282-87-6)
Recommended Standards
- 2-cyano-6-methylbenzene-1-sulfonyl chloride (CAS 1261824-69-4)
- Macitentan Impurity 28 (CAS 147000-89-3)
- 2-Cyano-4-methylbenzenesulfonyl chloride (CAS 1261682-98-7)
- 3-(cyanomethyl)benzene-1-sulfonyl chloride (CAS 1545937-52-7)
- Vitamin D3 Impurity 10 (CAS 216161-85-2)
- 1-Benzyl-7-bromoindolin-2-one (CAS 1447816-61-6)
- 1-(2-Fluorophenyl)-6-isopropyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1018127-29-1)
- 4-(6-CHLORO-2-IODOPYRIMIDIN-4-YL)MORPHOLINE (CAS 1072084-73-1)
- 2-(5-Chlorothiophene-2-carboxamido)-6-ethyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxamide hydrochloride (CAS 1215545-42-8)
- 2-Benzyloxy-benzoic Acid-13C3 Benzyl Ester (CAS 1330189-10-0)
- 2-Amino-N-(4-nitrophenyl)thiophene-3-carboxamide (CAS 667442-44-6)
- 4-Bromo-6-(difluoromethyl)-2,3-difluoropyridine (CAS 1804704-57-1)
- N-(3-methylbenzyl)thietan-3-amine (CAS 1782616-80-1)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
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