2-chloro-6-methanesulfonylbenzonitrile CAS 1443981-55-2
| CAS No. | 1443981-55-2 |
| Molecular Formula | C8H6ClNO2S |
| Molecular Weight | 215.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-chloro-6-methanesulfonylbenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-chloro-6-methanesulfonylbenzonitrile (CAS 1443981-55-2), a certified reference material (molecular formula C8H6ClNO2S, MW 215.66 g/mol) for analytical method development and quality control.
The molecular framework of 2-chloro-6-methanesulfonylbenzonitrile (C8H6ClNO2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNO2S |
| Molecular Weight | 215.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- Macitentan Impurity 28 (CAS 147000-89-3)
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- 2-cyano-6-methylbenzene-1-sulfonyl chloride (CAS 1261824-69-4)
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- Triethylene glycol monomethyl ether (CAS 112-35-6)
- (2S)-3-(Bromomethyl)but-3-en-2-ol (CAS 736158-13-7)
- (e)-3-(Furan-2-yl)-2-methylprop-2-en-1-ol (CAS 69978-22-9)
- 3,5-Dichloro-2-methylbenzylamine (CAS 1803813-26-4)
- (3-Methyl-1-phenyl-1h-pyrazol-4-yl)methanamine (CAS 1020718-05-1)
- 1-(5-Bromoisoindolin-2-yl)ethan-1-one (CAS 1380586-65-1)
- 1-(2-aminoethyl)-1H-imidazole-4-carboxylic acid hydrochloride (CAS 1955530-56-9)
- 2-(Ethylamino)benzonitrile (CAS 30091-24-8)
- Liraglutide Impurity 20 TFA Salt (CAS CATO-C4X-199220)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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