Quetiapine EP Impurity E CAS 1371638-05-9
| CAS No. | 1371638-05-9 |
| Molecular Formula | C40H44N6O2S2 |
| Molecular Weight | 704.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Quetiapine EP Impurity E meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Quetiapine EP Impurity E (CAS 1371638-05-9), a pharmacopoeial impurity reference standard (molecular formula C40H44N6O2S2, MW 704.95 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Quetiapine EP Impurity E is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 704.95 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C40H44N6O2S2 |
| Molecular Weight | 704.95 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Quetiapine Standards
- Quetiapine EP Impurity C (CAS 1798840-31-9)
- Quetiapine EP Impurity O (CAS 844639-06-1)
- Quetiapine EP Impurity W (CAS 1800608-95-0)
- Quetiapine EP Impurity N (CAS 1800291-86-4)
- Quetiapine EP Impurity D (CAS 945668-94-0)
- Quetiapine EP Impurity J (CAS 1356906-17-6)
- Quetiapine EP Impurity K (CAS 1371638-10-6)
- Quetiapine Impurity 3 (CAS CATO-C4X-12443)
Recommended Standards
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